RNA-editing ligase 1, mitochondrial · SINGLE PROTEIN · Trypanosoma brucei brucei
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As of 2026-09-14Protein identity stays anchored to UniProt P86926. Use UniProt P86926 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P86926 as the stable identity anchor, then attach disease evidence before program review.
RNA-editing ligase 1, mitochondrial
Review this target as RNA-editing ligase 1, mitochondrial, mapped to UniProt P86926. Sequence length is 469 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats RNA-editing ligase 1, mitochondrial as ChEMBL target CHEMBL4105928, mapped to UniProt P86926. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether RNA-editing ligase 1, mitochondrial is the right protein anchor across sources, using UniProt P86926 as the stable mapping.
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| Preferred Name | RNA-editing ligase 1, mitochondrial |
| Target Type | SINGLE PROTEIN |
| Organism | Trypanosoma brucei brucei |
| UniProt | P86926 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | RNA-editing ligase 1, mitochondrial |
| UniProt Accession | P86926 |
| Component Type | Protein |
| Sequence Length | 469 aa |
RNA-editing ligase 1, mitochondrial
Review this target as RNA-editing ligase 1, mitochondrial, mapped to UniProt P86926. Sequence length is 469 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL601757 | 6.39 | IC50 | 410.76 | Preclinical |
| CHEMBL1325945 | 6.31 | IC50 | 494.22 | Preclinical |
| CHEMBL1429070 | 5.56 | IC50 | 2759.0 | Preclinical |
| CHEMBL235504 | 5.46 | IC50 | 3510.0 | Preclinical |
| CHEMBL3561922 | 5.39 | IC50 | 4099.0 | Preclinical |
| CHEMBL1464200 | 5.3 | IC50 | 4989.0 | Preclinical |
| CHEMBL1470135 | 4.99 | IC50 | 10338.0 | Preclinical |
| CHEMBL1736648 | 4.91 | IC50 | 12331.0 | Preclinical |
| CHEMBL1501990 | 4.86 | IC50 | 13678.0 | Preclinical |
| CHEMBL1365833 | 4.83 | IC50 | 14741.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 38 | 4.7 |