Protein tyrosine phosphatase type IVA 3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt O75365. Use UniProt O75365 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O75365 as the stable identity anchor, then attach disease evidence before program review.
Protein tyrosine phosphatase type IVA 3
Review this target as Protein tyrosine phosphatase type IVA 3, mapped to UniProt O75365. Sequence length is 173 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Protein tyrosine phosphatase type IVA 3 as ChEMBL target CHEMBL4162, mapped to UniProt O75365. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Protein tyrosine phosphatase type IVA 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O75365 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Protein tyrosine phosphatase type IVA 3 |
| UniProt Accession | O75365 |
| Component Type | Protein |
| Sequence Length | 173 aa |
Protein tyrosine phosphatase type IVA 3
Review this target as Protein tyrosine phosphatase type IVA 3, mapped to UniProt O75365. Sequence length is 173 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4445621 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL4471843 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL4862721 | 6.97 | IC50 | 107.0 | Preclinical |
| CHEMBL3393171 | 6.89 | IC50 | 128.0 | Preclinical |
| CHEMBL4862502 | 6.69 | IC50 | 206.0 | Preclinical |
| CHEMBL55 | 6.52 | IC50 | 300.0 | Approved |
| CHEMBL2397162 | 6.1 | IC50 | 800.0 | Preclinical |
| CHEMBL207428 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL207958 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL4852178 | 5.94 | IC50 | 1160.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 25 | 3 | 4.5 |
| single protein format | 25 | 44 | 5.4 |
| assay format | 8 | 17 | 5.3 |