Use UniProt P97391 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4167 Target Snapshot
Phospholipase A2 group V · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P97391. Use UniProt P97391 as the stable identity anchor, then attach disease evidence before program review.
Phospholipase A2 group V
Review this target as Phospholipase A2 group V, mapped to UniProt P97391. Sequence length is 137 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Phospholipase A2 group V as ChEMBL target CHEMBL4167, mapped to UniProt P97391. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Phospholipase A2 group V is the right protein anchor across sources, using UniProt P97391 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Phospholipase A2 group V |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P97391 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phospholipase A2 group V |
| UniProt Accession | P97391 |
| Component Type | Protein |
| Sequence Length | 137 aa |
Phospholipase A2 group V
How to read this target
Review this target as Phospholipase A2 group V, mapped to UniProt P97391. Sequence length is 137 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5172164 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL515637 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL148649 | 7.24 | IC50 | 57.0 | Preclinical |
| CHEMBL514692 | 7.22 | IC50 | 60.0 | Preclinical |
| CHEMBL446349 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL332993 | 6.77 | IC50 | 170.0 | Preclinical |
| CHEMBL444450 | 6.28 | IC50 | 520.0 | Preclinical |
| CHEMBL148674 | 6.12 | IC50 | 750.0 | Clinical |
| CHEMBL208315 | 6.12 | IC50 | 750.0 | Preclinical |
| CHEMBL208429 | 6.07 | IC50 | 850.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 6 assays, 14 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 5 | 13 | 6.4 |
| assay format | 1 | 1 | 8.0 |