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Target Snapshot

CHEMBL4200 Target Snapshot

Group 10 secretory phospholipase A2 · SINGLE PROTEIN · Mus musculus

41Compounds
9Assays
0Approved Drugs
31.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q9QXX3. Use UniProt Q9QXX3 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9QXX3 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Group 10 secretory phospholipase A2 as ChEMBL target CHEMBL4200, mapped to UniProt Q9QXX3. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Group 10 secretory phospholipase A2
SINGLE PROTEIN · Mus musculus
As of 2026-09-14
ChEMBL target ID
CHEMBL4200
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q9QXX3
Group 10 secretory phospholipase A2
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Group 10 secretory phospholipase A2 is the right protein anchor across sources, using UniProt Q9QXX3 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelGroup 10 secretory phospholipase A2
UniProt AccessionQ9QXX3
Component TypeProtein
Sequence Length151 aa

Group 10 secretory phospholipase A2

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Group 10 secretory phospholipase A2, mapped to UniProt Q9QXX3. Sequence length is 151 aa.

Mapped IDQ9QXX3
Review nameGroup 10 secretory phospholipase A2
OrganismMus musculus
Clinical Profile

Clinical Phase Distribution

1
Phase II
Assay Mix

Activity Type Distribution

IC5031.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL515637 8.22 IC50 6.0 Preclinical
CHEMBL148649 7.7 IC50 20.0 Preclinical
CHEMBL514692 7.52 IC50 30.0 Preclinical
CHEMBL446349 7.46 IC50 35.0 Preclinical
CHEMBL148674 7.12 IC50 75.0 Clinical
CHEMBL208315 7.12 IC50 75.0 Preclinical
CHEMBL4215835 7.12 IC50 75.0 Preclinical
CHEMBL4171084 7.02 IC50 96.0 Preclinical
CHEMBL5172164 7.0 IC50 100.0 Preclinical
CHEMBL332993 6.05 IC50 900.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
2
5.5
1
6.0
0
6.5
7
7.0
2
7.5
1
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

9
Total Assays
12
Tested Compounds
2
Assay Types
Binding — 8 assays, 12 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 7 11 7.0
assay format 1 1 7.0
Functional — 1 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 1 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine