Group IID secretory phospholipase A2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9UNK4. Use UniProt Q9UNK4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UNK4 as the stable identity anchor, then attach disease evidence before program review.
Group IID secretory phospholipase A2
Review this target as Group IID secretory phospholipase A2, mapped to UniProt Q9UNK4. Sequence length is 145 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Group IID secretory phospholipase A2 as ChEMBL target CHEMBL4281, mapped to UniProt Q9UNK4. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Group IID secretory phospholipase A2 is the right protein anchor across sources, using UniProt Q9UNK4 as the stable mapping.
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| Preferred Name | Group IID secretory phospholipase A2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UNK4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Group IID secretory phospholipase A2 |
| UniProt Accession | Q9UNK4 |
| Component Type | Protein |
| Sequence Length | 145 aa |
Group IID secretory phospholipase A2
Review this target as Group IID secretory phospholipase A2, mapped to UniProt Q9UNK4. Sequence length is 145 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL515637 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL446349 | 7.46 | IC50 | 35.0 | Preclinical |
| CHEMBL148674 | 7.22 | IC50 | 60.0 | Clinical |
| CHEMBL514705 | 7.1 | IC50 | 80.0 | Preclinical |
| CHEMBL514841 | 7.1 | IC50 | 80.0 | Preclinical |
| CHEMBL148649 | 6.92 | IC50 | 120.0 | Preclinical |
| CHEMBL506485 | 6.77 | IC50 | 170.0 | Preclinical |
| CHEMBL514692 | 6.77 | IC50 | 170.0 | Preclinical |
| CHEMBL504813 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL479251 | 6.16 | IC50 | 700.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 5 | 5.6 |
| assay format | 1 | 10 | 7.0 |