Protein disulfide-isomerase A4 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P13667. Use UniProt P13667 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P13667 as the stable identity anchor, then attach disease evidence before program review.
Protein disulfide-isomerase A4
Review this target as Protein disulfide-isomerase A4, mapped to UniProt P13667. Sequence length is 645 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Protein disulfide-isomerase A4 as ChEMBL target CHEMBL4295717, mapped to UniProt P13667. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Protein disulfide-isomerase A4 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P13667 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Protein disulfide-isomerase A4 |
| UniProt Accession | P13667 |
| Component Type | Protein |
| Sequence Length | 645 aa |
Protein disulfide-isomerase A4
Review this target as Protein disulfide-isomerase A4, mapped to UniProt P13667. Sequence length is 645 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5653589 | 7.24 | Kd | 58.21 | Preclinical |
| CHEMBL43612 | 5.5 | IC50 | 3160.0 | Preclinical |
| CHEMBL5418475 | 5.4 | IC50 | 4010.0 | Preclinical |
| CHEMBL5399770 | 4.87 | IC50 | 13660.0 | Preclinical |
| CHEMBL4751979 | 4.48 | IC50 | 33100.0 | Preclinical |
| CHEMBL4751241 | 4.21 | IC50 | 61600.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 7 | 0 | — |
| single protein format | 3 | 4 | 5.8 |
| assay format | 1 | 2 | 4.3 |