Type IV secretion-like conjugative transfer relaxase protein TraI · SINGLE PROTEIN · Escherichia coli (strain SMS-3-5 / SECEC)
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As of 2026-09-14Protein identity stays anchored to UniProt B1LRJ1. Use UniProt B1LRJ1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt B1LRJ1 as the stable identity anchor, then attach disease evidence before program review.
Type IV secretion-like conjugative transfer relaxase protein TraI
Review this target as Type IV secretion-like conjugative transfer relaxase protein TraI, mapped to UniProt B1LRJ1. Sequence length is 1756 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Type IV secretion-like conjugative transfer relaxase protein TraI as ChEMBL target CHEMBL4296318, mapped to UniProt B1LRJ1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Type IV secretion-like conjugative transfer relaxase protein TraI |
| Target Type | SINGLE PROTEIN |
| Organism | Escherichia coli (strain SMS-3-5 / SECEC) |
| UniProt | B1LRJ1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Type IV secretion-like conjugative transfer relaxase protein TraI |
| UniProt Accession | B1LRJ1 |
| Component Type | Protein |
| Sequence Length | 1756 aa |
Type IV secretion-like conjugative transfer relaxase protein TraI
Review this target as Type IV secretion-like conjugative transfer relaxase protein TraI, mapped to UniProt B1LRJ1. Sequence length is 1756 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL265450 | 8.7 | Ki | 2.0 | Preclinical |
| CHEMBL12318 | 8.52 | Ki | 3.0 | Clinical |
| CHEMBL180570 | 8.52 | Ki | 3.0 | Clinical |
| CHEMBL871 | 8.52 | Ki | 3.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 5 | 4 | 8.6 |