Serine/threonine-protein phosphatase PP1-gamma catalytic subunit · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P36873. Use UniProt P36873 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P36873 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Review this target as Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, mapped to UniProt P36873. Sequence length is 323 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein phosphatase PP1-gamma catalytic subunit as ChEMBL target CHEMBL4438, mapped to UniProt P36873. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P36873 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit |
| UniProt Accession | P36873 |
| Component Type | Protein |
| Sequence Length | 323 aa |
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Review this target as Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, mapped to UniProt P36873. Sequence length is 323 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL444092 | 11.0 | IC50 | 0.01 | Preclinical |
| CHEMBL430266 | 9.85 | IC50 | 0.14 | Preclinical |
| CHEMBL1366322 | 8.8 | IC50 | 1.6 | Preclinical |
| CHEMBL408120 | 8.47 | Ki | 3.4 | Preclinical |
| CHEMBL406220 | 8.35 | Ki | 4.5 | Preclinical |
| CHEMBL405248 | 8.1 | Ki | 8.0 | Preclinical |
| CHEMBL261577 | 8.08 | Ki | 8.4 | Preclinical |
| CHEMBL427915 | 7.76 | Ki | 17.3 | Preclinical |
| CHEMBL406283 | 7.71 | Ki | 19.6 | Preclinical |
| CHEMBL280487 | 7.7 | IC50 | 20.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 33 | 24 | 7.6 |
| assay format | 1 | 0 | — |