Tyrosine-protein kinase Fgr · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P09769. Use UniProt P09769 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P09769 as the stable identity anchor, then attach disease evidence before program review.
Tyrosine-protein kinase Fgr
Review this target as Tyrosine-protein kinase Fgr, mapped to UniProt P09769. Sequence length is 529 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Tyrosine-protein kinase Fgr as ChEMBL target CHEMBL4454, mapped to UniProt P09769. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Tyrosine-protein kinase Fgr |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P09769 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tyrosine-protein kinase Fgr |
| UniProt Accession | P09769 |
| Component Type | Protein |
| Sequence Length | 529 aa |
Tyrosine-protein kinase Fgr
Review this target as Tyrosine-protein kinase Fgr, mapped to UniProt P09769. Sequence length is 529 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL249097 | 9.52 | Kd | 0.3 | Preclinical |
| CHEMBL3647967 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL5416410 | 9.3 | Kd | 0.5 | Approved |
| CHEMBL388978 | 9.18 | IC50 | 0.658 | Preclinical |
| CHEMBL364623 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL288441 | 8.96 | IC50 | 1.1 | Approved |
| CHEMBL1873475 | 8.74 | IC50 | 1.82 | Approved |
| CHEMBL2151321 | 8.66 | IC50 | 2.2 | Preclinical |
| CHEMBL386051 | 8.62 | Kd | 2.4 | Preclinical |
| CHEMBL2336005 | 8.43 | IC50 | 3.7 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 285 | 112 | 6.7 |
| assay format | 32 | 1 | 4.6 |
| cell-based format | 22 | 12 | 6.0 |
| subcellular format | 6 | 7 | 6.5 |
| cell membrane format | 1 | 1 | 8.4 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 2 | 7.8 |