Use UniProt Q07817 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4523705 Target Snapshot
Protein cereblon/Bcl-2-like protein 1 · PROTEIN-PROTEIN INTERACTION · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q07817. Use UniProt Q07817 as the stable identity anchor, then attach disease evidence before program review.
Bcl-2-like protein 1
Review this target as Protein cereblon/Bcl-2-like protein 1, mapped to UniProt Q07817. ChEMBL maps the protein component as Bcl-2-like protein 1. Sequence length is 233 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Protein cereblon/Bcl-2-like protein 1 as ChEMBL target CHEMBL4523705, mapped to UniProt Q07817. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Protein cereblon/Bcl-2-like protein 1 is the right protein anchor across sources, using UniProt Q07817 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Protein cereblon/Bcl-2-like protein 1 |
| Target Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
| UniProt | Q07817 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Bcl-2-like protein 1 |
| UniProt Accession | Q07817 |
| Component Type | Protein |
| Sequence Length | 233 aa |
Bcl-2-like protein 1
How to read this target
Review this target as Protein cereblon/Bcl-2-like protein 1, mapped to UniProt Q07817. ChEMBL maps the protein component as Bcl-2-like protein 1. Sequence length is 233 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5204319 | 7.34 | EC50 | 46.0 | Preclinical |
| CHEMBL4777606 | 7.3 | EC50 | 50.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 7 assays, 2 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 7 | 2 | 7.3 |