von Hippel-Lindau disease tumor suppressor/Androgen receptor · PROTEIN-PROTEIN INTERACTION · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P10275. Use UniProt P10275 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P10275 as the stable identity anchor, then attach disease evidence before program review.
Androgen receptor
Review this target as von Hippel-Lindau disease tumor suppressor/Androgen receptor, mapped to UniProt P10275. ChEMBL maps the protein component as Androgen receptor. Sequence length is 920 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats von Hippel-Lindau disease tumor suppressor/Androgen receptor as ChEMBL target CHEMBL4523730, mapped to UniProt P10275. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | von Hippel-Lindau disease tumor suppressor/Androgen receptor |
| Target Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
| UniProt | P10275 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Androgen receptor |
| UniProt Accession | P10275 |
| Component Type | Protein |
| Sequence Length | 920 aa |
Androgen receptor
Review this target as von Hippel-Lindau disease tumor suppressor/Androgen receptor, mapped to UniProt P10275. ChEMBL maps the protein component as Androgen receptor. Sequence length is 920 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4879244 | 10.0 | EC50 | 0.1 | Preclinical |
| CHEMBL4747369 | 9.7 | EC50 | 0.2 | Preclinical |
| CHEMBL4877348 | 9.52 | EC50 | 0.3 | Preclinical |
| CHEMBL4867584 | 9.4 | EC50 | 0.4 | Preclinical |
| CHEMBL4740749 | 9.12 | EC50 | 0.76 | Preclinical |
| CHEMBL4861919 | 9.1 | EC50 | 0.8 | Preclinical |
| CHEMBL5555109 | 6.67 | EC50 | 212.0 | Preclinical |
| CHEMBL4747580 | 6.43 | EC50 | 370.0 | Preclinical |
| CHEMBL5560053 | 6.28 | EC50 | 527.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 121 | 9 | 8.1 |
| assay format | 4 | 0 | — |
| protein format | 2 | 0 | — |
| tissue-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 1 | 0 | — |