Use UniProt Q5T601 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4523872 Target Snapshot
Adhesion G-protein coupled receptor F1 · SINGLE PROTEIN · Homo sapiens
Research home keeps recent targets
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Switch target
Move to another high-traffic target or paste a specific ChEMBL target ID.
Frame the target before identity details
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt Q5T601. Use UniProt Q5T601 as the stable identity anchor, then attach disease evidence before program review.
Adhesion G-protein coupled receptor F1
Review this target as Adhesion G-protein coupled receptor F1, mapped to UniProt Q5T601. Sequence length is 910 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Adhesion G-protein coupled receptor F1 as ChEMBL target CHEMBL4523872, mapped to UniProt Q5T601. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Start with the right source
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Adhesion G-protein coupled receptor F1 is the right protein anchor across sources, using UniProt Q5T601 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardBasic Information
Verify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Adhesion G-protein coupled receptor F1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q5T601 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Adhesion G-protein coupled receptor F1 |
| UniProt Accession | Q5T601 |
| Component Type | Protein |
| Sequence Length | 910 aa |
Adhesion G-protein coupled receptor F1
How to read this target
Review this target as Adhesion G-protein coupled receptor F1, mapped to UniProt Q5T601. Sequence length is 910 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL484929 | 5.69 | EC50 | 2041.85 | Preclinical |
| CHEMBL1707 | 5.69 | EC50 | 2040.77 | Approved |
| CHEMBL5092226 | 5.69 | IC50 | 2051.49 | Preclinical |
| CHEMBL1256876 | 5.58 | IC50 | 2598.51 | Preclinical |
| CHEMBL531742 | 5.55 | IC50 | 2839.13 | Preclinical |
| CHEMBL4743495 | 5.49 | IC50 | 3204.21 | Preclinical |
| CHEMBL1263 | 5.47 | IC50 | 3409.69 | Approved |
| CHEMBL5089005 | 5.41 | IC50 | 3893.51 | Preclinical |
| CHEMBL5075931 | 5.39 | IC50 | 4063.51 | Preclinical |
| CHEMBL1474387 | 5.3 | IC50 | 4996.8 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Functional — 5 assays, 11 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 0 | — |
| cell-based format | 2 | 11 | 5.5 |
Binding — 2 assays, 0 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 0 | — |