Secretory phospholipase A2 · PROTEIN FAMILY · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q5R387. Use UniProt Q5R387 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q5R387 as the stable identity anchor, then attach disease evidence before program review.
Putative inactive group IIC secretory phospholipase A2
Review this target as Secretory phospholipase A2, mapped to UniProt Q5R387. ChEMBL maps the protein component as Putative inactive group IIC secretory phospholipase A2. Sequence length is 149 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Secretory phospholipase A2 as ChEMBL target CHEMBL4524005, mapped to UniProt Q5R387. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Secretory phospholipase A2 is the right protein anchor across sources, using UniProt Q5R387 as the stable mapping.
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| Preferred Name | Secretory phospholipase A2 |
| Target Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
| UniProt | Q5R387 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Putative inactive group IIC secretory phospholipase A2 |
| UniProt Accession | Q5R387 |
| Component Type | Protein |
| Sequence Length | 149 aa |
Putative inactive group IIC secretory phospholipase A2
Review this target as Secretory phospholipase A2, mapped to UniProt Q5R387. ChEMBL maps the protein component as Putative inactive group IIC secretory phospholipase A2. Sequence length is 149 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4593409 | 7.25 | IC50 | 56.0 | Preclinical |
| CHEMBL148674 | 6.94 | IC50 | 114.0 | Clinical |
| CHEMBL4476621 | 4.7 | IC50 | 20000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 12 | 3 | 6.4 |
| cell-free format | 2 | 0 | — |
| cell-based format | 1 | 0 | — |