Cyclin-dependent kinase 16 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q00536. Use UniProt Q00536 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q00536 as the stable identity anchor, then attach disease evidence before program review.
Cyclin-dependent kinase 16
Review this target as Cyclin-dependent kinase 16, mapped to UniProt Q00536. Sequence length is 496 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cyclin-dependent kinase 16 as ChEMBL target CHEMBL4597, mapped to UniProt Q00536. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cyclin-dependent kinase 16 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q00536 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cyclin-dependent kinase 16 |
| UniProt Accession | Q00536 |
| Component Type | Protein |
| Sequence Length | 496 aa |
Cyclin-dependent kinase 16
Review this target as Cyclin-dependent kinase 16, mapped to UniProt Q00536. Sequence length is 496 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL384304 | 9.27 | Kd | 0.54 | Clinical |
| CHEMBL445813 | 8.96 | Kd | 1.1 | Clinical |
| CHEMBL3545083 | 8.52 | Kd | 3.0 | Preclinical |
| CHEMBL296468 | 8.15 | Kd | 7.1 | Preclinical |
| CHEMBL1082152 | 7.92 | Kd | 12.0 | Preclinical |
| CHEMBL2028663 | 7.89 | Kd | 13.0 | Approved |
| CHEMBL502835 | 7.68 | Kd | 21.0 | Approved |
| CHEMBL191003 | 7.64 | Kd | 23.0 | Preclinical |
| CHEMBL388978 | 7.62 | Kd | 24.0 | Preclinical |
| CHEMBL603469 | 7.57 | Kd | 27.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 102 | 45 | 6.3 |
| cell-based format | 26 | 0 | — |
| subcellular format | 25 | 28 | 6.4 |
| assay format | 21 | 0 | — |