Activated CDC42 kinase 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q07912. Use UniProt Q07912 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q07912 as the stable identity anchor, then attach disease evidence before program review.
Activated CDC42 kinase 1
Review this target as Activated CDC42 kinase 1, mapped to UniProt Q07912. Sequence length is 1038 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Activated CDC42 kinase 1 as ChEMBL target CHEMBL4599, mapped to UniProt Q07912. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Activated CDC42 kinase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q07912 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Activated CDC42 kinase 1 |
| UniProt Accession | Q07912 |
| Component Type | Protein |
| Sequence Length | 1038 aa |
Activated CDC42 kinase 1
Review this target as Activated CDC42 kinase 1, mapped to UniProt Q07912. Sequence length is 1038 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5400397 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL2087874 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL5408748 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL5431206 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL2087875 | 9.52 | Ki | 0.3 | Preclinical |
| CHEMBL2087873 | 9.52 | Ki | 0.3 | Preclinical |
| CHEMBL5409024 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL5398945 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL5419830 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL5428907 | 9.22 | IC50 | 0.6 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 236 | 500 | 6.6 |
| cell-based format | 55 | 116 | 7.9 |
| assay format | 36 | 63 | 7.0 |
| subcellular format | 15 | 28 | 6.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 115 | 6.1 |
| cell-based format | 1 | 1 | 5.6 |