Calcitonin gene-related peptide type 1 receptor · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q63118. Use UniProt Q63118 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q63118 as the stable identity anchor, then attach disease evidence before program review.
Calcitonin gene-related peptide type 1 receptor
Review this target as Calcitonin gene-related peptide type 1 receptor, mapped to UniProt Q63118. Sequence length is 464 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Calcitonin gene-related peptide type 1 receptor as ChEMBL target CHEMBL4755, mapped to UniProt Q63118. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Calcitonin gene-related peptide type 1 receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q63118 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Calcitonin gene-related peptide type 1 receptor |
| UniProt Accession | Q63118 |
| Component Type | Protein |
| Sequence Length | 464 aa |
Calcitonin gene-related peptide type 1 receptor
Review this target as Calcitonin gene-related peptide type 1 receptor, mapped to UniProt Q63118. Sequence length is 464 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL525571 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL2369463 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL2369459 | 8.62 | IC50 | 2.4 | Preclinical |
| CHEMBL2035981 | 8.47 | Ki | 3.4 | Preclinical |
| CHEMBL207197 | 8.47 | Ki | 3.4 | Clinical |
| CHEMBL197529 | 8.19 | IC50 | 6.4 | Preclinical |
| CHEMBL2369458 | 8.17 | IC50 | 6.8 | Preclinical |
| CHEMBL1910936 | 8.0 | Ki | 10.0 | Clinical |
| CHEMBL2369452 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL2369454 | 7.96 | IC50 | 11.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 3 | 16 | 8.0 |
| single protein format | 2 | 2 | 8.2 |
| tissue-based format | 2 | 4 | 7.0 |