Use UniProt Q60631 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4830 Target Snapshot
Growth factor receptor-bound protein 2 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt Q60631. Use UniProt Q60631 as the stable identity anchor, then attach disease evidence before program review.
Growth factor receptor-bound protein 2
Review this target as Growth factor receptor-bound protein 2, mapped to UniProt Q60631. Sequence length is 217 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Growth factor receptor-bound protein 2 as ChEMBL target CHEMBL4830, mapped to UniProt Q60631. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Growth factor receptor-bound protein 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q60631 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Growth factor receptor-bound protein 2 |
| UniProt Accession | Q60631 |
| Component Type | Protein |
| Sequence Length | 217 aa |
Growth factor receptor-bound protein 2
How to read this target
Review this target as Growth factor receptor-bound protein 2, mapped to UniProt Q60631. Sequence length is 217 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2369548 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL2369547 | 6.1 | IC50 | 800.0 | Preclinical |
| CHEMBL2369549 | 6.1 | IC50 | 800.0 | Preclinical |
| CHEMBL2372234 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL2372235 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL2372236 | 5.92 | IC50 | 1200.0 | Preclinical |
| CHEMBL2372231 | 5.82 | IC50 | 1500.0 | Preclinical |
| CHEMBL2372240 | 5.75 | IC50 | 1800.0 | Preclinical |
| CHEMBL2372239 | 5.7 | IC50 | 2000.0 | Preclinical |
| CHEMBL2372241 | 5.7 | IC50 | 2000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Functional — 3 assays, 0 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 0 | — |
Binding — 2 assays, 13 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 13 | 5.8 |