Compound Detail
CHEMBL2372239
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
COc1ccc(C[C@@H]2NC(=O)CN(C)C(=O)[C@@H]3CCCN3C(=O)[C@@H](C(C)C)NC(=O)[C@@H](NC(=O)c3c4nc5c(C(=O)N[C@@H]6C(=O)N[C@H](C(C)C)C(=O)N7CCC[C@H]7C(=O)N(C)CC(=O)N[C@@H](Cc7ccc(OC)cc7)C(=O)O[C@@H]6C)ccc(C)c5oc-4c(C)c(=O)c3N)[C@@H](C)OC2=O)cc1
Basic Information
| ChEMBL ID | CHEMBL2372239 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QHCJIZIAHVIVNW-ZOAGRWPPSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
1383.5
MW (Da)
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Growth factor receptor-bound protein 2 CHEMBL4830 | IC50 | 5.7 | 5.7 | 2000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Growth factor receptor-bound protein 2 | IC50 | = | 2000.0 | nM | 5.7 | In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor b... | 10888331 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10888331 | 10.1016/s0960-894x(00)00258-4 | Growth factor receptor-bound protein 2 | 3 |
| 10888331 | 10.1016/s0960-894x(00)00258-4 | B104 | 1 |
Data from ChEMBL 36 via Core Engine