Sterol 14alpha-demethylase · SINGLE PROTEIN · Mycobacterium tuberculosis
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As of 2026-09-13Protein identity stays anchored to UniProt P9WPP9. Use UniProt P9WPP9 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P9WPP9 as the stable identity anchor, then attach disease evidence before program review.
Sterol 14alpha-demethylase
Review this target as Sterol 14alpha-demethylase, mapped to UniProt P9WPP9. Sequence length is 451 aa.
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This review treats Sterol 14alpha-demethylase as ChEMBL target CHEMBL5090, mapped to UniProt P9WPP9. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sterol 14alpha-demethylase |
| Target Type | SINGLE PROTEIN |
| Organism | Mycobacterium tuberculosis |
| UniProt | P9WPP9 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sterol 14alpha-demethylase |
| UniProt Accession | P9WPP9 |
| Component Type | Protein |
| Sequence Length | 451 aa |
Sterol 14alpha-demethylase
Review this target as Sterol 14alpha-demethylase, mapped to UniProt P9WPP9. Sequence length is 451 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL91 | 6.7 | Kd | 200.0 | Approved |
| CHEMBL104 | 6.7 | Kd | 200.0 | Approved |
| CHEMBL106 | 6.7 | Kd | 200.0 | Approved |
| CHEMBL808 | 6.7 | Kd | 200.0 | Approved |
| CHEMBL14145 | 5.89 | Kd | 1300.0 | Preclinical |
| CHEMBL183282 | 5.3 | Kd | 5000.0 | Preclinical |
| CHEMBL507264 | 5.3 | Kd | 5000.0 | Preclinical |
| CHEMBL489925 | 5.3 | Kd | 5000.0 | Preclinical |
| CHEMBL490941 | 5.3 | Kd | 5000.0 | Preclinical |
| CHEMBL455684 | 5.3 | Kd | 5000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 13 | 4.9 |
| single protein format | 1 | 4 | 6.7 |