Breakpoint cluster region protein · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P11274. Use UniProt P11274 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P11274 as the stable identity anchor, then attach disease evidence before program review.
Breakpoint cluster region protein
Review this target as Breakpoint cluster region protein, mapped to UniProt P11274. Sequence length is 1271 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Breakpoint cluster region protein as ChEMBL target CHEMBL5146, mapped to UniProt P11274. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Breakpoint cluster region protein is the right protein anchor across sources, using UniProt P11274 as the stable mapping.
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| Preferred Name | Breakpoint cluster region protein |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P11274 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Breakpoint cluster region protein |
| UniProt Accession | P11274 |
| Component Type | Protein |
| Sequence Length | 1271 aa |
Breakpoint cluster region protein
Review this target as Breakpoint cluster region protein, mapped to UniProt P11274. Sequence length is 1271 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL400402 | 9.0 | Kd | 1.0 | Preclinical |
| CHEMBL288441 | 8.52 | Kd | 3.0 | Approved |
| CHEMBL3545085 | 8.52 | Kd | 3.0 | Preclinical |
| CHEMBL402548 | 8.3 | Kd | 5.0 | Clinical |
| CHEMBL5416410 | 8.3 | Kd | 5.0 | Approved |
| CHEMBL941 | 8.15 | Kd | 7.0 | Approved |
| CHEMBL3600873 | 7.96 | Kd | 11.0 | Preclinical |
| CHEMBL3688339 | 7.85 | Kd | 14.0 | Preclinical |
| CHEMBL206834 | 7.82 | Kd | 15.0 | Clinical |
| CHEMBL217092 | 7.8 | Kd | 16.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 18 | 0 | — |
| single protein format | 3 | 5 | 6.3 |
| assay format | 1 | 0 | — |
| subcellular format | 1 | 55 | 6.6 |