Nucleophosmin · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt P06748. Use UniProt P06748 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P06748 as the stable identity anchor, then attach disease evidence before program review.
Nucleophosmin
Review this target as Nucleophosmin, mapped to UniProt P06748. Sequence length is 294 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Nucleophosmin as ChEMBL target CHEMBL5178, mapped to UniProt P06748. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Nucleophosmin is the right protein anchor across sources, using UniProt P06748 as the stable mapping.
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| Preferred Name | Nucleophosmin |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P06748 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Nucleophosmin |
| UniProt Accession | P06748 |
| Component Type | Protein |
| Sequence Length | 294 aa |
Nucleophosmin
Review this target as Nucleophosmin, mapped to UniProt P06748. Sequence length is 294 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3752910 | 8.08 | Kd | 8.259 | Preclinical |
| CHEMBL1232461 | 8.0 | IC50 | 10.0 | Clinical |
| CHEMBL3589689 | 5.6 | EC50 | 2500.0 | Preclinical |
| CHEMBL593574 | 5.01 | EC50 | 9700.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 13 | 2 | 5.3 |
| single protein format | 7 | 3 | 8.0 |