Mitogen-activated protein kinase 15 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q8TD08. Use UniProt Q8TD08 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8TD08 as the stable identity anchor, then attach disease evidence before program review.
Mitogen-activated protein kinase 15
Review this target as Mitogen-activated protein kinase 15, mapped to UniProt Q8TD08. Sequence length is 544 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Mitogen-activated protein kinase 15 as ChEMBL target CHEMBL5198, mapped to UniProt Q8TD08. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Mitogen-activated protein kinase 15 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8TD08 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Mitogen-activated protein kinase 15 |
| UniProt Accession | Q8TD08 |
| Component Type | Protein |
| Sequence Length | 544 aa |
Mitogen-activated protein kinase 15
Review this target as Mitogen-activated protein kinase 15, mapped to UniProt Q8TD08. Sequence length is 544 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL603469 | 8.31 | Kd | 4.9 | Clinical |
| CHEMBL2048872 | 8.3 | Kd | 5.0 | Preclinical |
| CHEMBL388978 | 8.26 | Kd | 5.5 | Preclinical |
| CHEMBL388978 | 8.14 | IC50 | 7.3 | Preclinical |
| CHEMBL3752910 | 7.89 | Kd | 12.86 | Preclinical |
| CHEMBL384304 | 7.75 | Kd | 18.0 | Clinical |
| CHEMBL5653589 | 7.74 | Kd | 18.4 | Preclinical |
| CHEMBL4538174 | 7.52 | Kd | 30.0 | Preclinical |
| CHEMBL1082152 | 7.5 | Kd | 32.0 | Preclinical |
| CHEMBL1336 | 7.34 | Kd | 46.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 182 | 39 | 6.8 |
| assay format | 22 | 1 | 5.3 |
| cell-based format | 10 | 3 | 5.9 |
| subcellular format | 1 | 9 | 6.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |