Serine/threonine-protein kinase Nek9 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q8TD19. Use UniProt Q8TD19 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8TD19 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein kinase Nek9
Review this target as Serine/threonine-protein kinase Nek9, mapped to UniProt Q8TD19. Sequence length is 979 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein kinase Nek9 as ChEMBL target CHEMBL5257, mapped to UniProt Q8TD19. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Serine/threonine-protein kinase Nek9 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8TD19 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein kinase Nek9 |
| UniProt Accession | Q8TD19 |
| Component Type | Protein |
| Sequence Length | 979 aa |
Serine/threonine-protein kinase Nek9
Review this target as Serine/threonine-protein kinase Nek9, mapped to UniProt Q8TD19. Sequence length is 979 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL475251 | 7.8 | Kd | 16.0 | Clinical |
| CHEMBL5653589 | 7.64 | Kd | 22.91 | Preclinical |
| CHEMBL2103830 | 7.39 | Kd | 41.0 | Approved |
| CHEMBL2028663 | 7.28 | Kd | 53.0 | Approved |
| CHEMBL388978 | 7.15 | IC50 | 71.0 | Preclinical |
| CHEMBL3752910 | 7.14 | Kd | 71.81 | Preclinical |
| CHEMBL1078178 | 7.0 | IC50 | 100.0 | Approved |
| CHEMBL482967 | 6.88 | Kd | 133.0 | Preclinical |
| CHEMBL1287853 | 6.82 | Kd | 150.0 | Approved |
| CHEMBL3763358 | 6.42 | Kd | 380.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 161 | 21 | 6.2 |
| cell-based format | 34 | 0 | — |
| subcellular format | 33 | 15 | 6.1 |
| assay format | 23 | 0 | — |