Calcium/calmodulin-dependent protein kinase type 1G · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q96NX5. Use UniProt Q96NX5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q96NX5 as the stable identity anchor, then attach disease evidence before program review.
Calcium/calmodulin-dependent protein kinase type 1G
Review this target as Calcium/calmodulin-dependent protein kinase type 1G, mapped to UniProt Q96NX5. Sequence length is 476 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Calcium/calmodulin-dependent protein kinase type 1G as ChEMBL target CHEMBL5258, mapped to UniProt Q96NX5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Calcium/calmodulin-dependent protein kinase type 1G |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q96NX5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Calcium/calmodulin-dependent protein kinase type 1G |
| UniProt Accession | Q96NX5 |
| Component Type | Protein |
| Sequence Length | 476 aa |
Calcium/calmodulin-dependent protein kinase type 1G
Review this target as Calcium/calmodulin-dependent protein kinase type 1G, mapped to UniProt Q96NX5. Sequence length is 476 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4635883 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL522892 | 9.0 | Kd | 1.0 | Clinical |
| CHEMBL388978 | 8.4 | IC50 | 3.96 | Preclinical |
| CHEMBL388978 | 7.64 | Kd | 23.0 | Preclinical |
| CHEMBL3544964 | 6.93 | Kd | 117.0 | Clinical |
| CHEMBL502835 | 6.58 | Kd | 260.0 | Approved |
| CHEMBL4576489 | 6.52 | Kd | 302.0 | Preclinical |
| CHEMBL4465866 | 6.49 | Kd | 326.0 | Preclinical |
| CHEMBL535 | 6.36 | Kd | 440.0 | Approved |
| CHEMBL475251 | 6.34 | Kd | 460.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 112 | 23 | 6.3 |
| assay format | 18 | 0 | — |
| cell-based format | 4 | 3 | 6.8 |
| subcellular format | 1 | 2 | 8.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 1 | 8.0 |