Serine/threonine-protein kinase TAO1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q7L7X3. Use UniProt Q7L7X3 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q7L7X3 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein kinase TAO1
Review this target as Serine/threonine-protein kinase TAO1, mapped to UniProt Q7L7X3. Sequence length is 1001 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein kinase TAO1 as ChEMBL target CHEMBL5261, mapped to UniProt Q7L7X3. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Serine/threonine-protein kinase TAO1 is the right protein anchor across sources, using UniProt Q7L7X3 as the stable mapping.
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| Preferred Name | Serine/threonine-protein kinase TAO1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q7L7X3 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein kinase TAO1 |
| UniProt Accession | Q7L7X3 |
| Component Type | Protein |
| Sequence Length | 1001 aa |
Serine/threonine-protein kinase TAO1
Review this target as Serine/threonine-protein kinase TAO1, mapped to UniProt Q7L7X3. Sequence length is 1001 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL388978 | 9.35 | Kd | 0.45 | Preclinical |
| CHEMBL388978 | 9.33 | IC50 | 0.469 | Preclinical |
| CHEMBL3544966 | 8.7 | Kd | 2.0 | Preclinical |
| CHEMBL49120 | 8.2 | Ki | 6.31 | Preclinical |
| CHEMBL1980995 | 8.0 | Ki | 10.0 | Preclinical |
| CHEMBL5653589 | 7.93 | Kd | 11.86 | Preclinical |
| CHEMBL4576489 | 7.82 | Kd | 15.0 | Preclinical |
| CHEMBL2006715 | 7.8 | Ki | 15.85 | Preclinical |
| CHEMBL3688339 | 7.77 | Kd | 17.0 | Preclinical |
| CHEMBL2334586 | 7.7 | IC50 | 20.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 174 | 43 | 6.5 |
| assay format | 22 | 60 | 6.9 |
| cell-based format | 21 | 2 | 7.7 |
| subcellular format | 9 | 22 | 6.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 363 | 5.8 |