| Epidermal growth factor receptor CHEMBL203 | Ki | 8.7 | 8.7 | 2.0 | 1 |
| Tyrosine-protein kinase Lck CHEMBL258 | Ki | 8.6 | 8.6 | 2.5 | 1 |
| Receptor tyrosine-protein kinase erbB-2 CHEMBL1824 | Ki | 8.4 | 8.4 | 4.0 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 8.4 | 8.4 | 4.0 | 1 |
| Receptor tyrosine-protein kinase erbB-4 CHEMBL3009 | Ki | 8.0 | 8.0 | 10.0 | 1 |
| Aurora kinase A CHEMBL4722 | Ki | 8.0 | 8.0 | 10.0 | 1 |
| Proto-oncogene tyrosine-protein kinase receptor Ret CHEMBL2041 | Ki | 8.0 | 8.0 | 10.0 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 5 CHEMBL4852 | Ki | 7.9 | 7.9 | 12.6 | 1 |
| Proto-oncogene tyrosine-protein kinase Src CHEMBL267 | Ki | 7.9 | 7.9 | 12.6 | 1 |
| Serine/threonine-protein kinase TAO1 CHEMBL5261 | Ki | 7.8 | 7.8 | 15.8 | 1 |
| Tyrosine-protein kinase Lyn CHEMBL3905 | Ki | 7.8 | 7.8 | 15.8 | 1 |
| Tyrosine-protein kinase Srms CHEMBL5703 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| Tyrosine-protein kinase FRK CHEMBL4223 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| Tyrosine-protein kinase Fyn CHEMBL1841 | Ki | 7.5 | 7.5 | 31.6 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | Ki | 7.3 | 7.3 | 50.1 | 1 |
| Serine/threonine-protein kinase PLK3 CHEMBL4897 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| Tyrosine-protein kinase Blk CHEMBL2250 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| Insulin-like growth factor 1 receptor CHEMBL1957 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| Vascular endothelial growth factor receptor 3 CHEMBL1955 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| Mitogen-activated protein kinase 9 CHEMBL4179 | Ki | 7.0 | 7.0 | 100.0 | 1 |
| Mitogen-activated protein kinase kinase kinase 20 CHEMBL3886 | Ki | 7.0 | 7.0 | 100.0 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 7.0 | 7.0 | 100.0 | 1 |
| Serine/threonine-protein kinase 3 CHEMBL4708 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| STE20-like serine/threonine-protein kinase CHEMBL4202 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| Serine/threonine-protein kinase Nek2 CHEMBL3835 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Insulin receptor CHEMBL1981 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Tyrosine-protein kinase JAK3 CHEMBL2148 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Serine/threonine-protein kinase MRCK alpha CHEMBL4516 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| MAP kinase-activated protein kinase 5 CHEMBL3094 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 CHEMBL4045 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Tyrosine-protein kinase SYK CHEMBL2599 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| SRSF protein kinase 1 CHEMBL4375 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Serine/threonine-protein kinase Chk2 CHEMBL2527 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Serine/threonine-protein kinase D2 CHEMBL4900 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Testis-specific serine/threonine-protein kinase 1 CHEMBL6003 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| cGMP-dependent protein kinase 1 CHEMBL4273 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Maternal embryonic leucine zipper kinase CHEMBL4578 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 2 CHEMBL5330 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Mitogen-activated protein kinase 12 CHEMBL4674 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Tyrosine-protein kinase receptor TYRO3 CHEMBL5314 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Mitogen-activated protein kinase 1 CHEMBL4040 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| cGMP-dependent protein kinase 2 CHEMBL2896 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Homeodomain-interacting protein kinase 4 CHEMBL1075167 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Serine/threonine-protein kinase D3 CHEMBL2595 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Megakaryocyte-associated tyrosine-protein kinase CHEMBL4175 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Misshapen-like kinase 1 CHEMBL5518 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| High affinity nerve growth factor receptor CHEMBL2815 | Ki | 5.6 | 5.6 | 2511.9 | 1 |