Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1963807

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: STK12
ChEMBL ↗
999
Total Activities
983
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Aurora kinase B (CHEMBL2185) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 999 6.42 9.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1992195 — — 1 9.10
CHEMBL1980297 ILORASERTIB 2.0 1 9.10
CHEMBL1965170 — — 1 9.00
CHEMBL1985523 — — 1 8.90
CHEMBL243517 — — 1 8.90
CHEMBL1982837 — — 1 8.80
CHEMBL243749 — — 1 8.70
CHEMBL1980995 — — 1 8.70
CHEMBL243297 — — 1 8.70
CHEMBL482967 CYC-116 1.0 1 8.60
CHEMBL1965988 — — 1 8.60
CHEMBL1999414 — — 1 8.60
CHEMBL1988163 — — 1 8.60
CHEMBL1996649 — — 1 8.60
CHEMBL1993510 — — 1 8.60
CHEMBL1994321 — — 1 8.60
CHEMBL1972851 — — 1 8.50
CHEMBL1969190 — — 1 8.50
CHEMBL1972472 — — 1 8.50
CHEMBL1987034 — — 1 8.50
CHEMBL483158 ALISERTIB 3.0 1 8.50
CHEMBL1979577 — — 1 8.50
CHEMBL260092 — — 1 8.50
CHEMBL1988075 — — 1 8.40
CHEMBL396523 — — 1 8.40
CHEMBL1979093 — — 1 8.40
CHEMBL1999910 — — 1 8.40
CHEMBL411903 — — 1 8.40
CHEMBL1984162 — — 1 8.40
CHEMBL1973540 — — 1 8.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1980297 ILORASERTIB Ki = 0.7943 nM 9.10
CHEMBL1992195 — Ki = 0.7943 nM 9.10
CHEMBL1965170 — Ki = 1.0 nM 9.00
CHEMBL243517 — Ki = 1.259 nM 8.90
CHEMBL1985523 — Ki = 1.259 nM 8.90
CHEMBL1982837 — Ki = 1.585 nM 8.80
CHEMBL243297 — Ki = 1.995 nM 8.70
CHEMBL243749 — Ki = 1.995 nM 8.70
CHEMBL1980995 — Ki = 1.995 nM 8.70
CHEMBL1994321 — Ki = 2.512 nM 8.60
CHEMBL1999414 — Ki = 2.512 nM 8.60
CHEMBL1993510 — Ki = 2.512 nM 8.60
CHEMBL1988163 — Ki = 2.512 nM 8.60
CHEMBL1996649 — Ki = 2.512 nM 8.60
CHEMBL482967 CYC-116 Ki = 2.512 nM 8.60
CHEMBL1965988 — Ki = 2.512 nM 8.60
CHEMBL1972472 — Ki = 3.162 nM 8.50
CHEMBL483158 ALISERTIB Ki = 3.162 nM 8.50
CHEMBL1987034 — Ki = 3.162 nM 8.50
CHEMBL1979577 — Ki = 3.162 nM 8.50
CHEMBL260092 — Ki = 3.162 nM 8.50
CHEMBL1972851 — Ki = 3.162 nM 8.50
CHEMBL1969190 — Ki = 3.162 nM 8.50
CHEMBL2006715 — Ki = 3.981 nM 8.40
CHEMBL1973540 — Ki = 3.981 nM 8.40
CHEMBL1999910 — Ki = 3.981 nM 8.40
CHEMBL1988075 — Ki = 3.981 nM 8.40
CHEMBL1984162 — Ki = 3.981 nM 8.40
CHEMBL1979093 — Ki = 3.981 nM 8.40
CHEMBL411903 — Ki = 3.981 nM 8.40
CHEMBL396523 — Ki = 3.981 nM 8.40
CHEMBL1969834 — Ki = 5.012 nM 8.30
CHEMBL1966514 — Ki = 5.012 nM 8.30
CHEMBL415049 BARASERTIB Ki = 5.012 nM 8.30
CHEMBL1964519 — Ki = 5.012 nM 8.30
CHEMBL243518 — Ki = 5.012 nM 8.30
CHEMBL572878 TOZASERTIB Ki = 5.012 nM 8.30
CHEMBL1987658 — Ki = 6.31 nM 8.20
CHEMBL1241473 — Ki = 6.31 nM 8.20
CHEMBL1987910 — Ki = 6.31 nM 8.20
CHEMBL1991915 — Ki = 6.31 nM 8.20
CHEMBL1981725 — Ki = 6.31 nM 8.20
CHEMBL371206 — Ki = 6.31 nM 8.20
CHEMBL1971271 — Ki = 6.31 nM 8.20
CHEMBL1988769 — Ki = 7.943 nM 8.10
CHEMBL1971947 — Ki = 7.943 nM 8.10
CHEMBL1988437 — Ki = 7.943 nM 8.10
CHEMBL1964441 — Ki = 7.943 nM 8.10
CHEMBL2003604 — Ki = 7.943 nM 8.10
CHEMBL272453 — Ki = 7.943 nM 8.10