Tyrosine-protein kinase Srms · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9H3Y6. Use UniProt Q9H3Y6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9H3Y6 as the stable identity anchor, then attach disease evidence before program review.
Tyrosine-protein kinase Srms
Review this target as Tyrosine-protein kinase Srms, mapped to UniProt Q9H3Y6. Sequence length is 488 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Tyrosine-protein kinase Srms as ChEMBL target CHEMBL5703, mapped to UniProt Q9H3Y6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Tyrosine-protein kinase Srms |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9H3Y6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tyrosine-protein kinase Srms |
| UniProt Accession | Q9H3Y6 |
| Component Type | Protein |
| Sequence Length | 488 aa |
Tyrosine-protein kinase Srms
Review this target as Tyrosine-protein kinase Srms, mapped to UniProt Q9H3Y6. Sequence length is 488 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5416410 | 9.2 | Ki | 0.631 | Approved |
| CHEMBL1997617 | 8.2 | Ki | 6.31 | Preclinical |
| CHEMBL4108687 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL4106978 | 8.04 | IC50 | 9.1 | Preclinical |
| CHEMBL5416410 | 7.89 | Kd | 13.0 | Approved |
| CHEMBL4749037 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL4114929 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL1230609 | 7.75 | Kd | 18.0 | Clinical |
| CHEMBL4076024 | 7.72 | IC50 | 19.0 | Preclinical |
| CHEMBL1230020 | 7.68 | Kd | 21.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 136 | 40 | 6.5 |
| assay format | 25 | 0 | — |
| cell-based format | 7 | 1 | 7.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 49 | 6.5 |