| Tyrosine-protein kinase BTK CHEMBL5251 | Ki | 9.1 | 9.1 | 0.8 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 CHEMBL1974 | Ki | 8.8 | 8.8 | 1.6 | 1 |
| Protein-tyrosine kinase 6 CHEMBL4601 | Ki | 8.5 | 8.5 | 3.2 | 1 |
| Tyrosine-protein kinase ABL1 CHEMBL1862 | Ki | 8.4 | 8.4 | 4.0 | 1 |
| Tyrosine-protein kinase Srms CHEMBL5703 | Ki | 8.2 | 8.2 | 6.3 | 1 |
| Receptor tyrosine-protein kinase erbB-4 CHEMBL3009 | Ki | 8.1 | 8.1 | 7.9 | 1 |
| Proto-oncogene tyrosine-protein kinase receptor Ret CHEMBL2041 | Ki | 8.1 | 8.1 | 7.9 | 1 |
| Fibroblast growth factor receptor 1 CHEMBL3650 | Ki | 8.0 | 8.0 | 10.0 | 1 |
| Receptor tyrosine-protein kinase erbB-2 CHEMBL1824 | Ki | 7.9 | 7.9 | 12.6 | 1 |
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | Ki | 7.8 | 7.8 | 15.8 | 1 |
| Mast/stem cell growth factor receptor Kit CHEMBL1936 | Ki | 7.8 | 7.8 | 15.8 | 1 |
| Tyrosine-protein kinase ITK/TSK CHEMBL2959 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| Casein kinase I isoform delta CHEMBL2828 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| Fibroblast growth factor receptor 3 CHEMBL2742 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| Vascular endothelial growth factor receptor 3 CHEMBL1955 | Ki | 7.5 | 7.5 | 31.6 | 1 |
| Vascular endothelial growth factor receptor 1 CHEMBL1868 | Ki | 7.5 | 7.5 | 31.6 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | Ki | 7.5 | 7.5 | 31.6 | 1 |
| Epidermal growth factor receptor CHEMBL203 | Ki | 7.5 | 7.5 | 31.6 | 1 |
| Serine/threonine-protein kinase Chk2 CHEMBL2527 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 5 CHEMBL4852 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| Serine/threonine-protein kinase D2 CHEMBL4900 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| Tyrosine-protein kinase receptor UFO CHEMBL4895 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| Serine/threonine-protein kinase D3 CHEMBL2595 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Serine/threonine-protein kinase PAK 4 CHEMBL4482 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| ALK tyrosine kinase receptor CHEMBL4247 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Tyrosine-protein kinase Fer CHEMBL3982 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Serine/threonine-protein kinase 3 CHEMBL4708 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Serine/threonine-protein kinase MARK2 CHEMBL3831 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Insulin receptor CHEMBL1981 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| NT-3 growth factor receptor CHEMBL5608 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Serine/threonine-protein kinase PAK 1 CHEMBL4600 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Maternal embryonic leucine zipper kinase CHEMBL4578 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| LIM domain kinase 1 CHEMBL3836 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| MAP/microtubule affinity-regulating kinase 3 CHEMBL5600 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Interleukin-1 receptor-associated kinase 4 CHEMBL3778 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Ribosomal protein S6 kinase beta-1 CHEMBL4501 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Proto-oncogene tyrosine-protein kinase ROS CHEMBL5568 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| High affinity nerve growth factor receptor CHEMBL2815 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Protein kinase C delta type CHEMBL2996 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Serine/threonine-protein kinase MRCK alpha CHEMBL4516 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Mitogen-activated protein kinase kinase kinase 20 CHEMBL3886 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Serine/threonine-protein kinase Nek2 CHEMBL3835 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Casein kinase I isoform alpha CHEMBL2793 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| 3-phosphoinositide-dependent protein kinase 1 CHEMBL2534 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| BDNF/NT-3 growth factors receptor CHEMBL4898 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta CHEMBL2801 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| MAP kinase-interacting serine/threonine-protein kinase 2 CHEMBL4204 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Misshapen-like kinase 1 CHEMBL5518 | Ki | 5.6 | 5.6 | 2511.9 | 1 |