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Assay Detail

CHEMBL1964104

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CSF1R
ChEMBL ↗
979
Total Activities
959
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Macrophage colony-stimulating factor 1 receptor (CHEMBL1844) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 979 6.78 9.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL404366 — — 1 9.50
CHEMBL273187 — — 2 9.50
CHEMBL373798 — — 1 9.20
CHEMBL49120 PD-0166285 1.0 1 9.20
CHEMBL272938 — — 1 9.20
CHEMBL271441 — — 1 9.10
CHEMBL402846 — — 2 9.00
CHEMBL374044 — — 1 9.00
CHEMBL1993996 — — 1 8.90
CHEMBL1996255 — — 1 8.90
CHEMBL248757 — — 1 8.90
CHEMBL1994638 — — 1 8.80
CHEMBL403402 — — 1 8.80
CHEMBL1967116 — — 1 8.80
CHEMBL1982476 — — 1 8.80
CHEMBL1986979 — — 1 8.80
CHEMBL1986507 — — 1 8.70
CHEMBL196363 — — 1 8.70
CHEMBL1985491 — — 1 8.70
CHEMBL1970317 — — 1 8.70
CHEMBL1983963 — — 1 8.70
CHEMBL2000652 — — 2 8.70
CHEMBL1999414 — — 1 8.60
CHEMBL1974254 — — 1 8.60
CHEMBL1969102 — — 1 8.60
CHEMBL375284 — — 1 8.60
CHEMBL1996649 — — 1 8.60
CHEMBL1990885 — — 1 8.60
CHEMBL1985888 — — 1 8.60
CHEMBL1993941 — — 1 8.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL404366 — Ki = 0.3162 nM 9.50
CHEMBL273187 — Ki = 0.3162 nM 9.50
CHEMBL273187 — Ki = 0.3162 nM 9.50
CHEMBL272938 — Ki = 0.631 nM 9.20
CHEMBL373798 — Ki = 0.631 nM 9.20
CHEMBL49120 PD-0166285 Ki = 0.631 nM 9.20
CHEMBL271441 — Ki = 0.7943 nM 9.10
CHEMBL402846 — Ki = 1.0 nM 9.00
CHEMBL402846 — Ki = 1.0 nM 9.00
CHEMBL374044 — Ki = 1.0 nM 9.00
CHEMBL1993996 — Ki = 1.259 nM 8.90
CHEMBL1996255 — Ki = 1.259 nM 8.90
CHEMBL248757 — Ki = 1.259 nM 8.90
CHEMBL1967116 — Ki = 1.585 nM 8.80
CHEMBL1994638 — Ki = 1.585 nM 8.80
CHEMBL1982476 — Ki = 1.585 nM 8.80
CHEMBL403402 — Ki = 1.585 nM 8.80
CHEMBL1986979 — Ki = 1.585 nM 8.80
CHEMBL196363 — Ki = 1.995 nM 8.70
CHEMBL1986507 — Ki = 1.995 nM 8.70
CHEMBL2000652 — Ki = 1.995 nM 8.70
CHEMBL1985491 — Ki = 1.995 nM 8.70
CHEMBL1970317 — Ki = 1.995 nM 8.70
CHEMBL2000652 — Ki = 1.995 nM 8.70
CHEMBL1983963 — Ki = 1.995 nM 8.70
CHEMBL1996649 — Ki = 2.512 nM 8.60
CHEMBL1985888 — Ki = 2.512 nM 8.60
CHEMBL375284 — Ki = 2.512 nM 8.60
CHEMBL1969102 — Ki = 2.512 nM 8.60
CHEMBL1990885 — Ki = 2.512 nM 8.60
CHEMBL1999414 — Ki = 2.512 nM 8.60
CHEMBL1974254 — Ki = 2.512 nM 8.60
CHEMBL1980904 — Ki = 3.162 nM 8.50
CHEMBL1988778 — Ki = 3.162 nM 8.50
CHEMBL2002165 — Ki = 3.162 nM 8.50
CHEMBL1980297 ILORASERTIB Ki = 3.162 nM 8.50
CHEMBL2002446 — Ki = 3.162 nM 8.50
CHEMBL1973145 — Ki = 3.162 nM 8.50
CHEMBL2005631 — Ki = 3.162 nM 8.50
CHEMBL1993941 — Ki = 3.162 nM 8.50
CHEMBL2006778 — Ki = 3.981 nM 8.40
CHEMBL1968590 — Ki = 3.981 nM 8.40
CHEMBL1989708 — Ki = 3.981 nM 8.40
CHEMBL1966836 — Ki = 3.981 nM 8.40
CHEMBL220057 — Ki = 3.981 nM 8.40
CHEMBL1965170 — Ki = 3.981 nM 8.40
CHEMBL409349 — Ki = 3.981 nM 8.40
CHEMBL1975927 — Ki = 5.012 nM 8.30
CHEMBL1967720 — Ki = 5.012 nM 8.30
CHEMBL1985311 — Ki = 5.012 nM 8.30