Compound Detail
CHEMBL1980904
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Basic Information
| ChEMBL ID | CHEMBL1980904 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RKLGMDOZEOTQEM-UHFFFAOYSA-N |
12
Targets
12
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
429.4
MW (Da)
5.61
ALogP
3
HBA
4
HBD
95.8
PSA (Ų)
0.32
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 12 meas. best 9.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 1 CHEMBL1868 | Ki | 9.5 | 9.5 | 0.3 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | Ki | 9.1 | 9.1 | 0.8 | 1 |
| Mast/stem cell growth factor receptor Kit CHEMBL1936 | Ki | 8.6 | 8.6 | 2.5 | 1 |
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | Ki | 8.5 | 8.5 | 3.2 | 1 |
| Vascular endothelial growth factor receptor 3 CHEMBL1955 | Ki | 8.5 | 8.5 | 3.2 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 CHEMBL1974 | Ki | 8.5 | 8.5 | 3.2 | 1 |
| Tyrosine-protein kinase Lyn CHEMBL3905 | Ki | 7.4 | 7.4 | 39.8 | 1 |
| Tyrosine-protein kinase Fyn CHEMBL1841 | Ki | 7.0 | 7.0 | 100.0 | 1 |
| Proto-oncogene tyrosine-protein kinase Src CHEMBL267 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Tyrosine-protein kinase Lck CHEMBL258 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Tyrosine-protein kinase Blk CHEMBL2250 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Tyrosine-protein kinase ABL1 CHEMBL1862 | Ki | 6.5 | 6.5 | 316.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine