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Assay Detail

CHEMBL1963779

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: FLT3
ChEMBL ↗
956
Total Activities
940
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Receptor-type tyrosine-protein kinase FLT3 (CHEMBL1974) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 956 6.88 10.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL273187 — — 2 10.00
CHEMBL373798 — — 1 9.80
CHEMBL404366 — — 1 9.80
CHEMBL402846 — — 2 9.40
CHEMBL272938 — — 1 9.40
CHEMBL271441 — — 1 9.30
CHEMBL1996255 — — 1 9.10
CHEMBL196363 — — 1 9.10
CHEMBL1986979 — — 1 9.10
CHEMBL1968930 — — 1 9.10
CHEMBL374044 — — 1 9.00
CHEMBL1967720 — — 1 9.00
CHEMBL1994638 — — 1 9.00
CHEMBL1984363 — — 1 9.00
CHEMBL2000652 — — 2 9.00
CHEMBL403402 — — 1 9.00
CHEMBL1973178 — — 1 8.90
CHEMBL1967116 — — 1 8.90
CHEMBL1970317 — — 1 8.90
CHEMBL1998432 — — 1 8.90
CHEMBL1976220 — — 1 8.90
CHEMBL2005631 — — 1 8.80
CHEMBL1985888 — — 1 8.80
CHEMBL1990885 — — 1 8.80
CHEMBL2002446 — — 1 8.80
CHEMBL1983963 — — 1 8.80
CHEMBL411903 — — 1 8.80
CHEMBL262433 — — 1 8.80
CHEMBL1993996 — — 1 8.80
CHEMBL2005828 — — 1 8.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL273187 — Ki = 0.1 nM 10.00
CHEMBL273187 — Ki = 0.1 nM 10.00
CHEMBL404366 — Ki = 0.1585 nM 9.80
CHEMBL373798 — Ki = 0.1585 nM 9.80
CHEMBL402846 — Ki = 0.3981 nM 9.40
CHEMBL272938 — Ki = 0.3981 nM 9.40
CHEMBL402846 — Ki = 0.3981 nM 9.40
CHEMBL271441 — Ki = 0.5012 nM 9.30
CHEMBL1986979 — Ki = 0.7943 nM 9.10
CHEMBL1968930 — Ki = 0.7943 nM 9.10
CHEMBL1996255 — Ki = 0.7943 nM 9.10
CHEMBL196363 — Ki = 0.7943 nM 9.10
CHEMBL1967720 — Ki = 1.0 nM 9.00
CHEMBL2000652 — Ki = 1.0 nM 9.00
CHEMBL1994638 — Ki = 1.0 nM 9.00
CHEMBL1984363 — Ki = 1.0 nM 9.00
CHEMBL403402 — Ki = 1.0 nM 9.00
CHEMBL2000652 — Ki = 1.0 nM 9.00
CHEMBL374044 — Ki = 1.0 nM 9.00
CHEMBL1976220 — Ki = 1.259 nM 8.90
CHEMBL1967116 — Ki = 1.259 nM 8.90
CHEMBL1973178 — Ki = 1.259 nM 8.90
CHEMBL1970317 — Ki = 1.259 nM 8.90
CHEMBL1998432 — Ki = 1.259 nM 8.90
CHEMBL1997617 — Ki = 1.585 nM 8.80
CHEMBL1990885 — Ki = 1.585 nM 8.80
CHEMBL1985888 — Ki = 1.585 nM 8.80
CHEMBL1983963 — Ki = 1.585 nM 8.80
CHEMBL2005631 — Ki = 1.585 nM 8.80
CHEMBL262433 — Ki = 1.585 nM 8.80
CHEMBL1993996 — Ki = 1.585 nM 8.80
CHEMBL2002446 — Ki = 1.585 nM 8.80
CHEMBL2005828 — Ki = 1.585 nM 8.80
CHEMBL411903 — Ki = 1.585 nM 8.80
CHEMBL1968406 — Ki = 1.995 nM 8.70
CHEMBL1242373 — Ki = 1.995 nM 8.70
CHEMBL1988717 — Ki = 1.995 nM 8.70
CHEMBL394790 — Ki = 1.995 nM 8.70
CHEMBL1998585 — Ki = 1.995 nM 8.70
CHEMBL1966836 — Ki = 2.512 nM 8.60
CHEMBL404367 — Ki = 2.512 nM 8.60
CHEMBL409349 — Ki = 2.512 nM 8.60
CHEMBL1985491 — Ki = 2.512 nM 8.60
CHEMBL1965988 — Ki = 2.512 nM 8.60
CHEMBL213505 — Ki = 3.162 nM 8.50
CHEMBL220057 — Ki = 3.162 nM 8.50
CHEMBL1973540 — Ki = 3.162 nM 8.50
CHEMBL1967531 — Ki = 3.162 nM 8.50
CHEMBL1980904 — Ki = 3.162 nM 8.50
CHEMBL522892 DOVITINIB Ki = 3.162 nM 8.50