Compound Detail
CHEMBL1973178
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1973178 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UXQLMVSZSYZFID-UHFFFAOYSA-N |
12
Targets
12
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
458.4
MW (Da)
5.63
ALogP
6
HBA
3
HBD
111.6
PSA (Ų)
0.36
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 12 meas. best 9.2
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 1 CHEMBL1868 | Ki | 9.2 | 9.2 | 0.6 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | Ki | 9.0 | 9.0 | 1.0 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 CHEMBL1974 | Ki | 8.9 | 8.9 | 1.3 | 1 |
| Mast/stem cell growth factor receptor Kit CHEMBL1936 | Ki | 8.8 | 8.8 | 1.6 | 1 |
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | Ki | 8.3 | 8.3 | 5.0 | 1 |
| Vascular endothelial growth factor receptor 3 CHEMBL1955 | Ki | 7.9 | 7.9 | 12.6 | 1 |
| Tyrosine-protein kinase Blk CHEMBL2250 | Ki | 7.8 | 7.8 | 15.8 | 1 |
| Tyrosine-protein kinase Lck CHEMBL258 | Ki | 7.5 | 7.5 | 31.6 | 1 |
| Tyrosine-protein kinase Lyn CHEMBL3905 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| Tyrosine-protein kinase Fyn CHEMBL1841 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| Proto-oncogene tyrosine-protein kinase Src CHEMBL267 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| Tyrosine-protein kinase ABL1 CHEMBL1862 | Ki | 6.7 | 6.7 | 199.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine