| Tyrosine-protein kinase ABL1 CHEMBL1862 | Ki | 9.3 | 9.3 | 0.5 | 1 |
| Tyrosine-protein kinase Fyn CHEMBL1841 | Ki | 9.2 | 9.2 | 0.6 | 1 |
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | Ki | 8.8 | 8.8 | 1.6 | 1 |
| Proto-oncogene tyrosine-protein kinase Src CHEMBL267 | Ki | 8.7 | 8.7 | 2.0 | 1 |
| Tyrosine-protein kinase Lyn CHEMBL3905 | Ki | 8.6 | 8.6 | 2.5 | 1 |
| Aurora kinase A CHEMBL4722 | Ki | 8.5 | 8.5 | 3.2 | 1 |
| Tyrosine-protein kinase Blk CHEMBL2250 | Ki | 8.5 | 8.5 | 3.2 | 1 |
| Mast/stem cell growth factor receptor Kit CHEMBL1936 | Ki | 8.3 | 8.3 | 5.0 | 1 |
| BDNF/NT-3 growth factors receptor CHEMBL4898 | Ki | 8.2 | 8.2 | 6.3 | 1 |
| Fibroblast growth factor receptor 1 CHEMBL3650 | Ki | 8.2 | 8.2 | 6.3 | 1 |
| High affinity nerve growth factor receptor CHEMBL2815 | Ki | 8.1 | 8.1 | 7.9 | 1 |
| Ephrin type-A receptor 2 CHEMBL2068 | Ki | 8.0 | 8.0 | 10.0 | 1 |
| Hepatocyte growth factor receptor CHEMBL3717 | Ki | 8.0 | 8.0 | 10.0 | 1 |
| Tyrosine-protein kinase JAK2 CHEMBL2971 | Ki | 8.0 | 8.0 | 10.0 | 1 |
| Fibroblast growth factor receptor 3 CHEMBL2742 | Ki | 8.0 | 8.0 | 10.0 | 1 |
| Tyrosine-protein kinase Lck CHEMBL258 | Ki | 7.9 | 7.9 | 12.6 | 1 |
| Serine/threonine-protein kinase 3 CHEMBL4708 | Ki | 7.7 | 7.7 | 19.9 | 1 |
| Tyrosine-protein kinase ITK/TSK CHEMBL2959 | Ki | 7.5 | 7.5 | 31.6 | 1 |
| Serine/threonine-protein kinase PLK4 CHEMBL3788 | Ki | 7.4 | 7.4 | 39.8 | 1 |
| Ribosomal protein S6 kinase beta-1 CHEMBL4501 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| Tyrosine-protein kinase JAK3 CHEMBL2148 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| Receptor tyrosine-protein kinase erbB-2 CHEMBL1824 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| LIM domain kinase 1 CHEMBL3836 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Serine/threonine-protein kinase Nek2 CHEMBL3835 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Insulin receptor CHEMBL1981 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Rho-associated protein kinase 1 CHEMBL3231 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Serine/threonine-protein kinase MARK2 CHEMBL3831 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Non-receptor tyrosine-protein kinase TYK2 CHEMBL3553 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Death-associated protein kinase 3 CHEMBL2468 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Mitogen-activated protein kinase 9 CHEMBL4179 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| MAP/microtubule affinity-regulating kinase 3 CHEMBL5600 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Serine/threonine-protein kinase D2 CHEMBL4900 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Casein kinase I isoform delta CHEMBL2828 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Epidermal growth factor receptor CHEMBL203 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| 3-phosphoinositide-dependent protein kinase 1 CHEMBL2534 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Mitogen-activated protein kinase 13 CHEMBL2939 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Serine/threonine-protein kinase Sgk2 CHEMBL5794 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta CHEMBL1991 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Serine/threonine-protein kinase PAK 1 CHEMBL4600 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 CHEMBL4045 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| MAP kinase-activated protein kinase 2 CHEMBL2208 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| Protein kinase C delta type CHEMBL2996 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| Calcium/calmodulin-dependent protein kinase type 1 CHEMBL2493 | Ki | 5.1 | 5.1 | 7943.3 | 1 |