Assay Detail
Functional
CHEMBL1963708
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: RPS6KB1
698
Total Activities
690
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Category | other |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 698 | 6.28 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1998121 | — | — | 1 | 8.70 |
| CHEMBL491758 | — | — | 1 | 8.60 |
| CHEMBL220241 | GSK-269962A | — | 1 | 8.50 |
| CHEMBL1964413 | — | — | 1 | 8.40 |
| CHEMBL1980995 | — | — | 1 | 8.30 |
| CHEMBL1966524 | — | — | 1 | 8.20 |
| CHEMBL1965836 | — | — | 1 | 8.10 |
| CHEMBL272453 | — | — | 1 | 8.10 |
| CHEMBL1979577 | — | — | 1 | 8.10 |
| CHEMBL1967116 | — | — | 1 | 8.00 |
| CHEMBL1998159 | — | — | 1 | 7.90 |
| CHEMBL1964692 | — | — | 1 | 7.90 |
| CHEMBL2000335 | — | — | 1 | 7.90 |
| CHEMBL1968406 | — | — | 1 | 7.80 |
| CHEMBL1984432 | — | — | 1 | 7.80 |
| CHEMBL1987756 | — | — | 1 | 7.80 |
| CHEMBL1981782 | — | — | 1 | 7.80 |
| CHEMBL1994321 | — | — | 1 | 7.70 |
| CHEMBL1965988 | — | — | 1 | 7.70 |
| CHEMBL196363 | — | — | 1 | 7.70 |
| CHEMBL1998585 | — | — | 1 | 7.60 |
| CHEMBL1989708 | — | — | 2 | 7.60 |
| CHEMBL2004716 | — | — | 1 | 7.60 |
| CHEMBL1991063 | — | — | 1 | 7.60 |
| CHEMBL1976240 | — | — | 1 | 7.60 |
| CHEMBL1970083 | — | — | 1 | 7.60 |
| CHEMBL1970142 | — | — | 1 | 7.50 |
| CHEMBL1973211 | — | — | 1 | 7.50 |
| CHEMBL1969502 | — | — | 1 | 7.50 |
| CHEMBL1987679 | — | — | 1 | 7.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1998121 | — | Ki | = | 1.995 | nM | 8.70 |
| CHEMBL491758 | — | Ki | = | 2.512 | nM | 8.60 |
| CHEMBL220241 | GSK-269962A | Ki | = | 3.162 | nM | 8.50 |
| CHEMBL1964413 | — | Ki | = | 3.981 | nM | 8.40 |
| CHEMBL1980995 | — | Ki | = | 5.012 | nM | 8.30 |
| CHEMBL1966524 | — | Ki | = | 6.31 | nM | 8.20 |
| CHEMBL1965836 | — | Ki | = | 7.943 | nM | 8.10 |
| CHEMBL1979577 | — | Ki | = | 7.943 | nM | 8.10 |
| CHEMBL272453 | — | Ki | = | 7.943 | nM | 8.10 |
| CHEMBL1967116 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL1964692 | — | Ki | = | 12.59 | nM | 7.90 |
| CHEMBL2000335 | — | Ki | = | 12.59 | nM | 7.90 |
| CHEMBL1998159 | — | Ki | = | 12.59 | nM | 7.90 |
| CHEMBL1987756 | — | Ki | = | 15.85 | nM | 7.80 |
| CHEMBL1981782 | — | Ki | = | 15.85 | nM | 7.80 |
| CHEMBL1968406 | — | Ki | = | 15.85 | nM | 7.80 |
| CHEMBL1984432 | — | Ki | = | 15.85 | nM | 7.80 |
| CHEMBL1994321 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL196363 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1965988 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1998585 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1991063 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1976240 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1970083 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL2004716 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1989708 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1969502 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL1989708 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL1973211 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL1970142 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL1965845 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1979883 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL474432 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1242373 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1988387 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1987679 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1982466 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1983025 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1976220 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1979252 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1682357 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1964687 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL2001257 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1970709 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1682345 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL302449 | GO-6976 | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1982465 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL1969102 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL1988608 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL2004290 | — | Ki | = | 63.1 | nM | 7.20 |