| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | Ki | 8.4 | 8.4 | 4.0 | 1 |
| Ribosomal protein S6 kinase beta-1 CHEMBL4501 | Ki | 8.2 | 8.2 | 6.3 | 1 |
| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 8.0 | 8.0 | 10.0 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha CHEMBL4101 | Ki | 8.0 | 8.0 | 10.0 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 7.9 | 7.9 | 12.6 | 1 |
| RAC-alpha serine/threonine-protein kinase CHEMBL4282 | Ki | 7.9 | 7.9 | 12.6 | 1 |
| Rho-associated protein kinase 1 CHEMBL3231 | Ki | 7.7 | 7.7 | 19.9 | 1 |
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| RAC-gamma serine/threonine-protein kinase CHEMBL4816 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| Protein kinase C delta type CHEMBL2996 | Ki | 7.3 | 7.3 | 50.1 | 1 |
| Serine/threonine-protein kinase Sgk2 CHEMBL5794 | Ki | 7.3 | 7.3 | 50.1 | 1 |
| Death-associated protein kinase 3 CHEMBL2468 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| Vascular endothelial growth factor receptor 3 CHEMBL1955 | Ki | 7.0 | 7.0 | 100.0 | 1 |
| Cyclin-dependent kinase 1 CHEMBL308 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Protein kinase C zeta type CHEMBL3438 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Serine/threonine-protein kinase MRCK alpha CHEMBL4516 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| RAC-beta serine/threonine-protein kinase CHEMBL2431 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 CHEMBL1974 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| 3-phosphoinositide-dependent protein kinase 1 CHEMBL2534 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Mitogen-activated protein kinase 1 CHEMBL4040 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Serine/threonine-protein kinase D2 CHEMBL4900 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 CHEMBL4045 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Vascular endothelial growth factor receptor 1 CHEMBL1868 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Cyclin-dependent kinase 5 CHEMBL4036 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Serine/threonine-protein kinase MARK2 CHEMBL3831 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Protein kinase C gamma type CHEMBL2938 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| MAP/microtubule affinity-regulating kinase 3 CHEMBL5600 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Serine/threonine-protein kinase Chk2 CHEMBL2527 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Casein kinase II subunit alpha CHEMBL3629 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Serine/threonine-protein kinase PLK4 CHEMBL3788 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Mast/stem cell growth factor receptor Kit CHEMBL1936 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| LIM domain kinase 1 CHEMBL3836 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Casein kinase I isoform delta CHEMBL2828 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Serine/threonine-protein kinase PLK3 CHEMBL4897 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Serine/threonine-protein kinase 3 CHEMBL4708 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Serine/threonine-protein kinase PAK 1 CHEMBL4600 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Tyrosine-protein kinase JAK2 CHEMBL2971 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Interleukin-1 receptor-associated kinase 4 CHEMBL3778 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Epidermal growth factor receptor CHEMBL203 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Mitogen-activated protein kinase 12 CHEMBL4674 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Mitogen-activated protein kinase 8 CHEMBL2276 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Fibroblast growth factor receptor 1 CHEMBL3650 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Calcium/calmodulin-dependent protein kinase type 1 CHEMBL2493 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Serine/threonine-protein kinase Chk1 CHEMBL4630 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Serine/threonine-protein kinase PAK 4 CHEMBL4482 | Ki | 5.3 | 5.3 | 5011.9 | 1 |