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Assay Detail

CHEMBL1963793

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: SGK
ChEMBL ↗
740
Total Activities
731
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Serine/threonine-protein kinase Sgk2 (CHEMBL5794) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 740 5.85 8.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1980995 — — 1 8.10
CHEMBL1973540 — — 1 7.80
CHEMBL1965845 — — 1 7.70
CHEMBL1998121 — — 1 7.70
CHEMBL2001751 — — 1 7.60
CHEMBL1969502 — — 1 7.40
CHEMBL1997534 — — 1 7.30
CHEMBL1970903 — — 1 7.30
CHEMBL1966524 — — 1 7.30
CHEMBL1966628 — — 1 7.30
CHEMBL1975128 — — 1 7.20
CHEMBL1998159 — — 1 7.20
CHEMBL1999931 — — 1 7.20
CHEMBL1991063 — — 1 7.10
CHEMBL2003638 — — 1 7.00
CHEMBL1969042 — — 1 7.00
CHEMBL1982957 — — 1 6.90
CHEMBL1999811 — — 1 6.90
CHEMBL1986943 — — 2 6.80
CHEMBL1988608 — — 1 6.80
CHEMBL1976090 — — 1 6.80
CHEMBL2006933 — — 1 6.80
CHEMBL1974870 — — 1 6.80
CHEMBL220241 GSK-269962A — 1 6.70
CHEMBL1241473 — — 1 6.70
CHEMBL1970217 — — 1 6.70
CHEMBL244378 — — 1 6.70
CHEMBL1971943 BAY-549 — 1 6.60
CHEMBL482967 CYC-116 1.0 1 6.60
CHEMBL1725279 SP-600125 — 1 6.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1980995 — Ki = 7.943 nM 8.10
CHEMBL1973540 — Ki = 15.85 nM 7.80
CHEMBL1965845 — Ki = 19.95 nM 7.70
CHEMBL1998121 — Ki = 19.95 nM 7.70
CHEMBL2001751 — Ki = 25.12 nM 7.60
CHEMBL1969502 — Ki = 39.81 nM 7.40
CHEMBL1966524 — Ki = 50.12 nM 7.30
CHEMBL1970903 — Ki = 50.12 nM 7.30
CHEMBL1997534 — Ki = 50.12 nM 7.30
CHEMBL1966628 — Ki = 50.12 nM 7.30
CHEMBL1998159 — Ki = 63.1 nM 7.20
CHEMBL1999931 — Ki = 63.1 nM 7.20
CHEMBL1975128 — Ki = 63.1 nM 7.20
CHEMBL1991063 — Ki = 79.43 nM 7.10
CHEMBL2003638 — Ki = 100.0 nM 7.00
CHEMBL1969042 — Ki = 100.0 nM 7.00
CHEMBL1982957 — Ki = 125.89 nM 6.90
CHEMBL1999811 — Ki = 125.89 nM 6.90
CHEMBL1988608 — Ki = 158.49 nM 6.80
CHEMBL2006933 — Ki = 158.49 nM 6.80
CHEMBL1974870 — Ki = 158.49 nM 6.80
CHEMBL1986943 — Ki = 158.49 nM 6.80
CHEMBL1986943 — Ki = 158.49 nM 6.80
CHEMBL1976090 — Ki = 158.49 nM 6.80
CHEMBL244378 — Ki = 199.53 nM 6.70
CHEMBL1241473 — Ki = 199.53 nM 6.70
CHEMBL220241 GSK-269962A Ki = 199.53 nM 6.70
CHEMBL1970217 — Ki = 199.53 nM 6.70
CHEMBL482967 CYC-116 Ki = 251.19 nM 6.60
CHEMBL1682345 — Ki = 251.19 nM 6.60
CHEMBL1982711 — Ki = 251.19 nM 6.60
CHEMBL1976240 — Ki = 251.19 nM 6.60
CHEMBL1725279 SP-600125 Ki = 251.19 nM 6.60
CHEMBL1966343 — Ki = 251.19 nM 6.60
CHEMBL1971943 BAY-549 Ki = 251.19 nM 6.60
CHEMBL1972346 — Ki = 316.23 nM 6.50
CHEMBL1965836 — Ki = 316.23 nM 6.50
CHEMBL1989646 — Ki = 316.23 nM 6.50
CHEMBL1992342 — Ki = 316.23 nM 6.50
CHEMBL2004934 — Ki = 316.23 nM 6.50
CHEMBL1969049 — Ki = 316.23 nM 6.50
CHEMBL1990254 — Ki = 316.23 nM 6.50
CHEMBL1990885 — Ki = 316.23 nM 6.50
CHEMBL1986263 — Ki = 316.23 nM 6.50
CHEMBL1969588 — Ki = 398.11 nM 6.40
CHEMBL1964937 — Ki = 398.11 nM 6.40
CHEMBL1975121 — Ki = 398.11 nM 6.40
CHEMBL1983111 — Ki = 398.11 nM 6.40
CHEMBL1985311 — Ki = 398.11 nM 6.40
CHEMBL1988537 — Ki = 398.11 nM 6.40