| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 7.4 | 7.4 | 39.8 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| cGMP-dependent protein kinase 1 CHEMBL4273 | Ki | 7.0 | 7.0 | 100.0 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha CHEMBL4101 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 CHEMBL4045 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Tyrosine-protein kinase receptor UFO CHEMBL4895 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Ribosomal protein S6 kinase alpha-5 CHEMBL4237 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Serine/threonine-protein kinase N2 CHEMBL3032 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Rho-associated protein kinase 1 CHEMBL3231 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Ribosomal protein S6 kinase beta-1 CHEMBL4501 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Serine/threonine-protein kinase Sgk2 CHEMBL5794 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| cGMP-dependent protein kinase 2 CHEMBL2896 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 2 CHEMBL5330 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Misshapen-like kinase 1 CHEMBL5518 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Mitogen-activated protein kinase 1 CHEMBL4040 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Testis-specific serine/threonine-protein kinase 1 CHEMBL6003 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 CHEMBL1974 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Serine/threonine-protein kinase 17A CHEMBL4525 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Dual specificity protein kinase CLK2 CHEMBL4225 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Serine/threonine-protein kinase Chk2 CHEMBL2527 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Serine/threonine-protein kinase D2 CHEMBL4900 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Maternal embryonic leucine zipper kinase CHEMBL4578 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Tyrosine-protein kinase JAK3 CHEMBL2148 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Serine/threonine-protein kinase Chk1 CHEMBL4630 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Protein kinase C delta type CHEMBL2996 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Serine/threonine-protein kinase BRSK1 CHEMBL5650 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 5 CHEMBL4852 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Cyclin-dependent kinase 1 CHEMBL308 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| MAP kinase-interacting serine/threonine-protein kinase 2 CHEMBL4204 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Tyrosine-protein kinase FRK CHEMBL4223 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Protein kinase C gamma type CHEMBL2938 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Serine/threonine-protein kinase MRCK alpha CHEMBL4516 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Serine/threonine-protein kinase 3 CHEMBL4708 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| STE20-like serine/threonine-protein kinase CHEMBL4202 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Cyclin-dependent kinase 5 CHEMBL4036 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Interleukin-1 receptor-associated kinase 4 CHEMBL3778 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Vascular endothelial growth factor receptor 3 CHEMBL1955 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Serine/threonine-protein kinase Nek4 CHEMBL5819 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| MAP/microtubule affinity-regulating kinase 3 CHEMBL5600 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Serine/threonine-protein kinase MARK2 CHEMBL3831 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Homeodomain-interacting protein kinase 2 CHEMBL4576 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Homeodomain-interacting protein kinase 4 CHEMBL1075167 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Fibroblast growth factor receptor 1 CHEMBL3650 | Ki | 5.3 | 5.3 | 5011.9 | 1 |