Assay Detail
Functional
CHEMBL1963748
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: PKN2
698
Total Activities
686
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Category | other |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 698 | 6.30 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1980995 | — | — | 1 | 9.10 |
| CHEMBL1998432 | — | — | 1 | 8.60 |
| CHEMBL1969588 | — | — | 1 | 8.60 |
| CHEMBL1968930 | — | — | 1 | 8.60 |
| CHEMBL1972290 | — | — | 1 | 8.30 |
| CHEMBL225519 | — | — | 1 | 8.30 |
| CHEMBL1970903 | — | — | 1 | 8.30 |
| CHEMBL2001751 | — | — | 1 | 8.30 |
| CHEMBL1994977 | — | — | 1 | 8.20 |
| CHEMBL1973540 | — | — | 1 | 8.20 |
| CHEMBL1986943 | — | — | 2 | 8.10 |
| CHEMBL2006456 | — | — | 1 | 8.00 |
| CHEMBL1969151 | — | — | 1 | 8.00 |
| CHEMBL1991674 | — | — | 1 | 7.90 |
| CHEMBL1997534 | — | — | 1 | 7.80 |
| CHEMBL1974870 | — | — | 1 | 7.80 |
| CHEMBL1996980 | — | — | 1 | 7.80 |
| CHEMBL1987261 | — | — | 1 | 7.70 |
| CHEMBL1985723 | — | — | 1 | 7.70 |
| CHEMBL1965660 | — | — | 2 | 7.70 |
| CHEMBL1976936 | — | — | 1 | 7.70 |
| CHEMBL1974935 | — | — | 1 | 7.70 |
| CHEMBL1998121 | — | — | 1 | 7.70 |
| CHEMBL1991063 | — | — | 1 | 7.70 |
| CHEMBL1964290 | — | — | 1 | 7.60 |
| CHEMBL1998159 | — | — | 1 | 7.60 |
| CHEMBL220241 | GSK-269962A | — | 1 | 7.60 |
| CHEMBL1965845 | — | — | 1 | 7.60 |
| CHEMBL2005509 | — | — | 1 | 7.60 |
| CHEMBL1981133 | — | — | 1 | 7.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1980995 | — | Ki | = | 0.7943 | nM | 9.10 |
| CHEMBL1969588 | — | Ki | = | 2.512 | nM | 8.60 |
| CHEMBL1968930 | — | Ki | = | 2.512 | nM | 8.60 |
| CHEMBL1998432 | — | Ki | = | 2.512 | nM | 8.60 |
| CHEMBL2001751 | — | Ki | = | 5.012 | nM | 8.30 |
| CHEMBL1972290 | — | Ki | = | 5.012 | nM | 8.30 |
| CHEMBL225519 | — | Ki | = | 5.012 | nM | 8.30 |
| CHEMBL1970903 | — | Ki | = | 5.012 | nM | 8.30 |
| CHEMBL1973540 | — | Ki | = | 6.31 | nM | 8.20 |
| CHEMBL1994977 | — | Ki | = | 6.31 | nM | 8.20 |
| CHEMBL1986943 | — | Ki | = | 7.943 | nM | 8.10 |
| CHEMBL1986943 | — | Ki | = | 7.943 | nM | 8.10 |
| CHEMBL1969151 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL2006456 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL1991674 | — | Ki | = | 12.59 | nM | 7.90 |
| CHEMBL1997534 | — | Ki | = | 15.85 | nM | 7.80 |
| CHEMBL1996980 | — | Ki | = | 15.85 | nM | 7.80 |
| CHEMBL1974870 | — | Ki | = | 15.85 | nM | 7.80 |
| CHEMBL1965660 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1998121 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1965660 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1991063 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1985723 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1987261 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1976936 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1974935 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1964290 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL2005509 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL220241 | GSK-269962A | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1965845 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1998159 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL340384 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL1981133 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL1992220 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1990482 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1969502 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1976240 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1980178 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1997129 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1982271 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1994669 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1978271 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1988608 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL2005718 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1967878 | CENISERTIB | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1990254 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1984548 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1990254 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1965836 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL1981079 | — | Ki | = | 63.1 | nM | 7.20 |