| Cell division cycle 7-related protein kinase CHEMBL5443 | Ki | 9.5 | 9.5 | 0.3 | 1 |
| Rho-associated protein kinase 1 CHEMBL3231 | Ki | 8.9 | 8.9 | 1.3 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 8.6 | 8.6 | 2.5 | 1 |
| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 8.6 | 8.6 | 2.5 | 1 |
| Maternal embryonic leucine zipper kinase CHEMBL4578 | Ki | 8.5 | 8.5 | 3.2 | 1 |
| Cyclin-dependent kinase 9 CHEMBL3116 | Ki | 8.3 | 8.3 | 5.0 | 1 |
| Protein kinase C theta type CHEMBL3920 | Ki | 8.1 | 8.1 | 7.9 | 1 |
| Cyclin-dependent kinase 5 CHEMBL4036 | Ki | 8.0 | 8.0 | 10.0 | 1 |
| Serine/threonine-protein kinase N2 CHEMBL3032 | Ki | 8.0 | 8.0 | 10.0 | 1 |
| Leucine-rich repeat serine/threonine-protein kinase 2 CHEMBL1075104 | Ki | 7.8 | 7.8 | 15.8 | 1 |
| Serine/threonine-protein kinase D3 CHEMBL2595 | Ki | 7.8 | 7.8 | 15.8 | 1 |
| Cyclin-dependent kinase 8 CHEMBL5719 | Ki | 7.8 | 7.8 | 15.8 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha CHEMBL4101 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| cAMP-dependent protein kinase catalytic subunit PRKX CHEMBL5818 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B CHEMBL5543 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| Misshapen-like kinase 1 CHEMBL5518 | Ki | 7.5 | 7.5 | 31.6 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | Ki | 7.4 | 7.4 | 39.8 | 1 |
| Dual specificity protein kinase CLK2 CHEMBL4225 | Ki | 7.4 | 7.4 | 39.8 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 7.4 | 7.4 | 39.8 | 1 |
| Serine/threonine-protein kinase PAK 4 CHEMBL4482 | Ki | 7.3 | 7.3 | 50.1 | 1 |
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| Homeodomain-interacting protein kinase 2 CHEMBL4576 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| Death-associated protein kinase 3 CHEMBL2468 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| Serine/threonine-protein kinase 3 CHEMBL4708 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 CHEMBL4045 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| Macrophage-stimulating protein receptor CHEMBL2689 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| Cyclin-dependent kinase 7 CHEMBL3055 | Ki | 7.0 | 7.0 | 100.0 | 1 |
| Serine/threonine-protein kinase 17A CHEMBL4525 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 5 CHEMBL4852 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 1 CHEMBL3587 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Casein kinase I isoform alpha CHEMBL2793 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 2 CHEMBL2964 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 2 CHEMBL5330 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha CHEMBL4147 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Leukocyte tyrosine kinase receptor CHEMBL5627 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| G protein-coupled receptor kinase 5 CHEMBL5678 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Platelet-derived growth factor receptor beta CHEMBL1913 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Mitogen-activated protein kinase 8 CHEMBL2276 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Tyrosine-protein kinase JAK2 CHEMBL2971 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta CHEMBL2801 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| ALK tyrosine kinase receptor CHEMBL4247 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 CHEMBL1974 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Tyrosine-protein kinase JAK3 CHEMBL2148 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 5.8 | 5.8 | 1584.9 | 1 |