Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1963715

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: PRKCN
ChEMBL ↗
902
Total Activities
884
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Serine/threonine-protein kinase D3 (CHEMBL2595) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 902 5.97 8.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1997129 — — 1 8.40
CHEMBL1974870 — — 1 8.40
CHEMBL1991063 — — 1 8.40
CHEMBL1986263 — — 1 8.40
CHEMBL1994669 — — 1 8.30
CHEMBL1970903 — — 1 8.30
CHEMBL1973720 — — 2 8.30
CHEMBL2005509 — — 1 8.30
CHEMBL1966628 — — 1 8.20
CHEMBL2001751 — — 1 8.20
CHEMBL1984548 — — 1 8.10
CHEMBL1971029 — — 1 8.10
CHEMBL1983589 — — 1 8.00
CHEMBL1965423 — — 1 8.00
CHEMBL1992220 — — 1 8.00
CHEMBL1972290 — — 1 7.90
CHEMBL1980407 — — 1 7.80
CHEMBL244378 — — 1 7.80
CHEMBL1986943 — — 2 7.80
CHEMBL1969151 — — 1 7.80
CHEMBL396523 — — 1 7.80
CHEMBL340384 — — 1 7.70
CHEMBL1982874 — — 1 7.70
CHEMBL1987034 — — 1 7.50
CHEMBL1965836 — — 1 7.50
CHEMBL1998432 — — 1 7.50
CHEMBL1190711 — — 1 7.50
CHEMBL509032 TAE-684 — 1 7.50
CHEMBL1980995 — — 1 7.40
CHEMBL1981725 — — 1 7.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1997129 — Ki = 3.981 nM 8.40
CHEMBL1974870 — Ki = 3.981 nM 8.40
CHEMBL1986263 — Ki = 3.981 nM 8.40
CHEMBL1991063 — Ki = 3.981 nM 8.40
CHEMBL2005509 — Ki = 5.012 nM 8.30
CHEMBL1970903 — Ki = 5.012 nM 8.30
CHEMBL1994669 — Ki = 5.012 nM 8.30
CHEMBL1973720 — Ki = 5.012 nM 8.30
CHEMBL1973720 — Ki = 5.012 nM 8.30
CHEMBL2001751 — Ki = 6.31 nM 8.20
CHEMBL1966628 — Ki = 6.31 nM 8.20
CHEMBL1984548 — Ki = 7.943 nM 8.10
CHEMBL1971029 — Ki = 7.943 nM 8.10
CHEMBL1983589 — Ki = 10.0 nM 8.00
CHEMBL1965423 — Ki = 10.0 nM 8.00
CHEMBL1992220 — Ki = 10.0 nM 8.00
CHEMBL1972290 — Ki = 12.59 nM 7.90
CHEMBL396523 — Ki = 15.85 nM 7.80
CHEMBL1986943 — Ki = 15.85 nM 7.80
CHEMBL1969151 — Ki = 15.85 nM 7.80
CHEMBL1986943 — Ki = 15.85 nM 7.80
CHEMBL244378 — Ki = 15.85 nM 7.80
CHEMBL1980407 — Ki = 15.85 nM 7.80
CHEMBL340384 — Ki = 19.95 nM 7.70
CHEMBL1982874 — Ki = 19.95 nM 7.70
CHEMBL509032 TAE-684 Ki = 31.62 nM 7.50
CHEMBL1987034 — Ki = 31.62 nM 7.50
CHEMBL1998432 — Ki = 31.62 nM 7.50
CHEMBL1965836 — Ki = 31.62 nM 7.50
CHEMBL1190711 — Ki = 31.62 nM 7.50
CHEMBL1993661 — Ki = 39.81 nM 7.40
CHEMBL1981725 — Ki = 39.81 nM 7.40
CHEMBL1980995 — Ki = 39.81 nM 7.40
CHEMBL1999484 — Ki = 50.12 nM 7.30
CHEMBL1996980 — Ki = 50.12 nM 7.30
CHEMBL2006456 — Ki = 50.12 nM 7.30
CHEMBL1967878 CENISERTIB Ki = 50.12 nM 7.30
CHEMBL2004419 — Ki = 50.12 nM 7.30
CHEMBL1967998 — Ki = 50.12 nM 7.30
CHEMBL1990288 — Ki = 63.1 nM 7.20
CHEMBL1988163 — Ki = 63.1 nM 7.20
CHEMBL49120 PD-0166285 Ki = 63.1 nM 7.20
CHEMBL1965660 — Ki = 63.1 nM 7.20
CHEMBL1987448 — Ki = 63.1 nM 7.20
CHEMBL1965660 — Ki = 63.1 nM 7.20
CHEMBL1982957 — Ki = 63.1 nM 7.20
CHEMBL243298 — Ki = 63.1 nM 7.20
CHEMBL1980253 — Ki = 79.43 nM 7.10
CHEMBL2005718 — Ki = 79.43 nM 7.10
CHEMBL1995813 — Ki = 79.43 nM 7.10