Serine/threonine-protein kinase Sgk2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9HBY8. Use UniProt Q9HBY8 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9HBY8 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein kinase Sgk2
Review this target as Serine/threonine-protein kinase Sgk2, mapped to UniProt Q9HBY8. Sequence length is 367 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein kinase Sgk2 as ChEMBL target CHEMBL5794, mapped to UniProt Q9HBY8. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Serine/threonine-protein kinase Sgk2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9HBY8 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein kinase Sgk2 |
| UniProt Accession | Q9HBY8 |
| Component Type | Protein |
| Sequence Length | 367 aa |
Serine/threonine-protein kinase Sgk2
Review this target as Serine/threonine-protein kinase Sgk2, mapped to UniProt Q9HBY8. Sequence length is 367 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1980995 | 8.1 | Ki | 7.943 | Preclinical |
| CHEMBL388978 | 7.82 | IC50 | 15.1 | Preclinical |
| CHEMBL1973540 | 7.8 | Ki | 15.85 | Preclinical |
| CHEMBL1998121 | 7.7 | Ki | 19.95 | Preclinical |
| CHEMBL1965845 | 7.7 | Ki | 19.95 | Preclinical |
| CHEMBL5082336 | 7.68 | IC50 | 21.0 | Preclinical |
| CHEMBL2001751 | 7.6 | Ki | 25.12 | Preclinical |
| CHEMBL1969502 | 7.4 | Ki | 39.81 | Preclinical |
| CHEMBL1966628 | 7.3 | Ki | 50.12 | Preclinical |
| CHEMBL1966524 | 7.3 | Ki | 50.12 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 145 | 7 | 6.9 |
| assay format | 32 | 0 | — |
| cell-based format | 8 | 2 | 5.8 |
| subcellular format | 5 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 253 | 5.8 |