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Assay Detail

CHEMBL1963819

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CDC2
ChEMBL ↗
743
Total Activities
729
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Cyclin-dependent kinase 1 (CHEMBL308) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 743 6.13 8.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1977223 — — 1 8.40
CHEMBL1980995 — — 1 8.40
CHEMBL1999931 — — 1 8.30
CHEMBL1966628 — — 1 8.20
CHEMBL1995740 — — 1 8.20
CHEMBL2003638 — — 1 8.00
CHEMBL1990583 — — 1 7.80
CHEMBL302449 GO-6976 — 1 7.80
CHEMBL1986263 — — 1 7.70
CHEMBL1973540 — — 1 7.70
CHEMBL1241473 — — 1 7.70
CHEMBL1987034 — — 1 7.60
CHEMBL1969588 — — 1 7.60
CHEMBL50894 ALSTERPAULLONE — 1 7.50
CHEMBL2006439 — — 1 7.50
CHEMBL422897 — — 2 7.50
CHEMBL592030 — — 1 7.50
CHEMBL1965507 — — 1 7.50
CHEMBL1998159 — — 1 7.50
CHEMBL1975128 — — 2 7.50
CHEMBL1986943 — — 2 7.40
CHEMBL1974870 — — 2 7.40
CHEMBL1985406 — — 1 7.40
CHEMBL1983111 — — 1 7.40
CHEMBL1991078 — — 1 7.40
CHEMBL1982711 — — 1 7.40
CHEMBL1975418 — — 1 7.40
CHEMBL1971029 — — 1 7.40
CHEMBL1988163 — — 1 7.30
CHEMBL1970903 — — 1 7.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1980995 — Ki = 3.981 nM 8.40
CHEMBL1977223 — Ki = 3.981 nM 8.40
CHEMBL1999931 — Ki = 5.012 nM 8.30
CHEMBL1995740 — Ki = 6.31 nM 8.20
CHEMBL1966628 — Ki = 6.31 nM 8.20
CHEMBL2003638 — Ki = 10.0 nM 8.00
CHEMBL1990583 — Ki = 15.85 nM 7.80
CHEMBL302449 GO-6976 Ki = 15.85 nM 7.80
CHEMBL1986263 — Ki = 19.95 nM 7.70
CHEMBL1973540 — Ki = 19.95 nM 7.70
CHEMBL1241473 — Ki = 19.95 nM 7.70
CHEMBL1987034 — Ki = 25.12 nM 7.60
CHEMBL1969588 — Ki = 25.12 nM 7.60
CHEMBL592030 — Ki = 31.62 nM 7.50
CHEMBL2006439 — Ki = 31.62 nM 7.50
CHEMBL50894 ALSTERPAULLONE Ki = 31.62 nM 7.50
CHEMBL422897 — Ki = 31.62 nM 7.50
CHEMBL1975128 — Ki = 31.62 nM 7.50
CHEMBL1998159 — Ki = 31.62 nM 7.50
CHEMBL1975128 — Ki = 31.62 nM 7.50
CHEMBL422897 — Ki = 31.62 nM 7.50
CHEMBL1965507 — Ki = 31.62 nM 7.50
CHEMBL1986943 — Ki = 39.81 nM 7.40
CHEMBL1974870 — Ki = 39.81 nM 7.40
CHEMBL1983111 — Ki = 39.81 nM 7.40
CHEMBL1986943 — Ki = 39.81 nM 7.40
CHEMBL1971029 — Ki = 39.81 nM 7.40
CHEMBL1991078 — Ki = 39.81 nM 7.40
CHEMBL1982711 — Ki = 39.81 nM 7.40
CHEMBL1974870 — Ki = 39.81 nM 7.40
CHEMBL1985406 — Ki = 39.81 nM 7.40
CHEMBL1975418 — Ki = 39.81 nM 7.40
CHEMBL1991063 — Ki = 50.12 nM 7.30
CHEMBL1970903 — Ki = 50.12 nM 7.30
CHEMBL1988594 — Ki = 50.12 nM 7.30
CHEMBL1988163 — Ki = 50.12 nM 7.30
CHEMBL1976455 — Ki = 63.1 nM 7.20
CHEMBL1965660 — Ki = 63.1 nM 7.20
CHEMBL1982957 — Ki = 63.1 nM 7.20
CHEMBL1965660 — Ki = 63.1 nM 7.20
CHEMBL1084546 PF-00562271 Ki = 63.1 nM 7.20
CHEMBL244378 — Ki = 79.43 nM 7.10
CHEMBL2000832 — Ki = 79.43 nM 7.10
CHEMBL1970203 — Ki = 79.43 nM 7.10
CHEMBL396523 — Ki = 79.43 nM 7.10
CHEMBL1981720 — Ki = 79.43 nM 7.10
CHEMBL1969561 — Ki = 100.0 nM 7.00
CHEMBL1965631 — Ki = 100.0 nM 7.00
CHEMBL1965836 — Ki = 100.0 nM 7.00
CHEMBL2006933 — Ki = 125.89 nM 6.90