Compound Detail
CHEMBL1970709
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Basic Information
| ChEMBL ID | CHEMBL1970709 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NPLQZQGAZAUUTB-UHFFFAOYSA-N |
9
Targets
9
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
345.2
MW (Da)
3.65
ALogP
2
HBA
3
HBD
69.8
PSA (Ų)
0.68
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 9 meas. best 8.9
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| cAMP-dependent protein kinase catalytic subunit PRKX CHEMBL5818 | Ki | 8.9 | 8.9 | 1.3 | 1 |
| Ribosomal protein S6 kinase alpha-5 CHEMBL4237 | Ki | 7.3 | 7.3 | 50.1 | 1 |
| Ribosomal protein S6 kinase beta-1 CHEMBL4501 | Ki | 7.3 | 7.3 | 50.1 | 1 |
| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 7.0 | 7.0 | 100.0 | 1 |
| cGMP-dependent protein kinase 2 CHEMBL2896 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha CHEMBL4101 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Rho-associated protein kinase 1 CHEMBL3231 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Serine/threonine-protein kinase Sgk2 CHEMBL5794 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine