Assay Detail
Functional
CHEMBL1964119
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: STK3
819
Total Activities
809
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Category | other |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 819 | 6.22 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1980995 | — | — | 1 | 9.40 |
| CHEMBL1997924 | — | — | 1 | 8.80 |
| CHEMBL1994669 | — | — | 1 | 8.50 |
| CHEMBL1984548 | — | — | 1 | 8.40 |
| CHEMBL1976936 | — | — | 1 | 8.10 |
| CHEMBL1971029 | — | — | 1 | 8.00 |
| CHEMBL1977148 | — | — | 1 | 7.90 |
| CHEMBL2001751 | — | — | 1 | 7.90 |
| CHEMBL1967878 | CENISERTIB | 2.0 | 1 | 7.90 |
| CHEMBL1980297 | ILORASERTIB | 2.0 | 1 | 7.80 |
| CHEMBL1982476 | — | — | 1 | 7.70 |
| CHEMBL1967116 | — | — | 1 | 7.70 |
| CHEMBL379975 | — | — | 1 | 7.60 |
| CHEMBL1970317 | — | — | 1 | 7.60 |
| CHEMBL1973395 | — | — | 1 | 7.60 |
| CHEMBL1982466 | — | — | 1 | 7.50 |
| CHEMBL1241473 | — | — | 1 | 7.50 |
| CHEMBL1998432 | — | — | 1 | 7.50 |
| CHEMBL1974254 | — | — | 1 | 7.50 |
| CHEMBL2002165 | — | — | 1 | 7.50 |
| CHEMBL2002649 | — | — | 1 | 7.50 |
| CHEMBL1970142 | — | — | 1 | 7.50 |
| CHEMBL1986855 | — | — | 1 | 7.50 |
| CHEMBL1968930 | — | — | 1 | 7.40 |
| CHEMBL1980391 | RG-1530 | 1.0 | 1 | 7.40 |
| CHEMBL1966628 | — | — | 1 | 7.40 |
| CHEMBL1990583 | — | — | 1 | 7.40 |
| CHEMBL2005216 | — | — | 1 | 7.40 |
| CHEMBL1992220 | — | — | 1 | 7.30 |
| CHEMBL1986943 | — | — | 2 | 7.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1980995 | — | Ki | = | 0.3981 | nM | 9.40 |
| CHEMBL1997924 | — | Ki | = | 1.585 | nM | 8.80 |
| CHEMBL1994669 | — | Ki | = | 3.162 | nM | 8.50 |
| CHEMBL1984548 | — | Ki | = | 3.981 | nM | 8.40 |
| CHEMBL1976936 | — | Ki | = | 7.943 | nM | 8.10 |
| CHEMBL1971029 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL1967878 | CENISERTIB | Ki | = | 12.59 | nM | 7.90 |
| CHEMBL2001751 | — | Ki | = | 12.59 | nM | 7.90 |
| CHEMBL1977148 | — | Ki | = | 12.59 | nM | 7.90 |
| CHEMBL1980297 | ILORASERTIB | Ki | = | 15.85 | nM | 7.80 |
| CHEMBL1967116 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL1982476 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL379975 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1973395 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1970317 | — | Ki | = | 25.12 | nM | 7.60 |
| CHEMBL1998432 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL1974254 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL1970142 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL1241473 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL2002649 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL1982466 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL1986855 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL2002165 | — | Ki | = | 31.62 | nM | 7.50 |
| CHEMBL1968930 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL2005216 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1980391 | RG-1530 | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1966628 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1990583 | — | Ki | = | 39.81 | nM | 7.40 |
| CHEMBL1986943 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1983111 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1966842 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1983589 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1970903 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1969102 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1991674 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL373598 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL413779 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1989708 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1992220 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1986943 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL1979516 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL2005509 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL2005886 | — | Ki | = | 50.12 | nM | 7.30 |
| CHEMBL2006778 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL223367 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL1989708 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL1991063 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL2005631 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL1970203 | — | Ki | = | 63.1 | nM | 7.20 |
| CHEMBL248757 | — | Ki | = | 63.1 | nM | 7.20 |