| Vascular endothelial growth factor receptor 1 CHEMBL1868 | Ki | 9.6 | 9.6 | 0.3 | 1 |
| Tyrosine-protein kinase ABL1 CHEMBL1862 | Ki | 9.2 | 9.2 | 0.6 | 1 |
| Tyrosine-protein kinase Lck CHEMBL258 | Ki | 8.8 | 8.8 | 1.6 | 1 |
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | Ki | 8.6 | 8.6 | 2.5 | 1 |
| NT-3 growth factor receptor CHEMBL5608 | Ki | 8.6 | 8.6 | 2.5 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | Ki | 8.4 | 8.4 | 4.0 | 1 |
| Tyrosine-protein kinase Blk CHEMBL2250 | Ki | 8.3 | 8.3 | 5.0 | 1 |
| Tyrosine-protein kinase Lyn CHEMBL3905 | Ki | 8.2 | 8.2 | 6.3 | 1 |
| Mast/stem cell growth factor receptor Kit CHEMBL1936 | Ki | 8.1 | 8.1 | 7.9 | 1 |
| Aurora kinase A CHEMBL4722 | Ki | 8.0 | 8.0 | 10.0 | 1 |
| Tyrosine-protein kinase Fyn CHEMBL1841 | Ki | 7.9 | 7.9 | 12.6 | 1 |
| Proto-oncogene tyrosine-protein kinase Src CHEMBL267 | Ki | 7.8 | 7.8 | 15.8 | 1 |
| Tyrosine-protein kinase receptor UFO CHEMBL4895 | Ki | 7.8 | 7.8 | 15.8 | 1 |
| Tyrosine-protein kinase Fer CHEMBL3982 | Ki | 7.7 | 7.7 | 19.9 | 1 |
| Serine/threonine-protein kinase 3 CHEMBL4708 | Ki | 7.5 | 7.5 | 31.6 | 1 |
| Hepatocyte growth factor receptor CHEMBL3717 | Ki | 7.5 | 7.5 | 31.6 | 1 |
| Fibroblast growth factor receptor 1 CHEMBL3650 | Ki | 7.5 | 7.5 | 31.6 | 1 |
| Tyrosine-protein kinase FRK CHEMBL4223 | Ki | 7.3 | 7.3 | 50.1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| High affinity nerve growth factor receptor CHEMBL2815 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| Tyrosine-protein kinase BTK CHEMBL5251 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| BDNF/NT-3 growth factors receptor CHEMBL4898 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| Serine/threonine-protein kinase PLK4 CHEMBL3788 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 2 CHEMBL5330 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Misshapen-like kinase 1 CHEMBL5518 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Tyrosine-protein kinase SYK CHEMBL2599 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Homeodomain-interacting protein kinase 4 CHEMBL1075167 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Ribosomal protein S6 kinase beta-1 CHEMBL4501 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Insulin receptor CHEMBL1981 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Ribosomal protein S6 kinase alpha-5 CHEMBL4237 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| STE20-like serine/threonine-protein kinase CHEMBL4202 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Rho-associated protein kinase 1 CHEMBL3231 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Tyrosine-protein kinase Fes/Fps CHEMBL5455 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Ephrin type-A receptor 2 CHEMBL2068 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Protein-tyrosine kinase 2-beta CHEMBL5469 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Death-associated protein kinase 3 CHEMBL2468 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| cAMP-dependent protein kinase catalytic subunit PRKX CHEMBL5818 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Serine/threonine-protein kinase pim-2 CHEMBL4523 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Lymphokine-activated killer T-cell-originated protein kinase CHEMBL4896 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Serine/threonine-protein kinase Nek2 CHEMBL3835 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Serine/threonine-protein kinase PLK3 CHEMBL4897 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| MAP kinase-interacting serine/threonine-protein kinase 2 CHEMBL4204 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Serine/threonine-protein kinase TAO1 CHEMBL5261 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| MAP kinase-activated protein kinase 2 CHEMBL2208 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Serine/threonine-protein kinase MARK2 CHEMBL3831 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Serine/threonine-protein kinase MRCK alpha CHEMBL4516 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| LIM domain kinase 1 CHEMBL3836 | Ki | 5.0 | 5.0 | 10000.0 | 1 |
| Interleukin-1 receptor-associated kinase 4 CHEMBL3778 | Ki | 5.0 | 5.0 | 10000.0 | 1 |