Potassium voltage-gated channel subfamily A member 6 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P17658. Use UniProt P17658 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P17658 as the stable identity anchor, then attach disease evidence before program review.
Potassium voltage-gated channel subfamily A member 6
Review this target as Potassium voltage-gated channel subfamily A member 6, mapped to UniProt P17658. Sequence length is 529 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Potassium voltage-gated channel subfamily A member 6 as ChEMBL target CHEMBL5279, mapped to UniProt P17658. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Potassium voltage-gated channel subfamily A member 6 is the right protein anchor across sources, using UniProt P17658 as the stable mapping.
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| Preferred Name | Potassium voltage-gated channel subfamily A member 6 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P17658 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Potassium voltage-gated channel subfamily A member 6 |
| UniProt Accession | P17658 |
| Component Type | Protein |
| Sequence Length | 529 aa |
Potassium voltage-gated channel subfamily A member 6
Review this target as Potassium voltage-gated channel subfamily A member 6, mapped to UniProt P17658. Sequence length is 529 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL444449 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL4207745 | 5.8 | IC50 | 1600.0 | Preclinical |
| CHEMBL3621636 | 5.43 | IC50 | 3700.0 | Preclinical |
| CHEMBL397591 | 5.31 | IC50 | 4900.0 | Preclinical |
| CHEMBL3261431 | 5.1 | IC50 | 7900.0 | Preclinical |
| CHEMBL4213446 | 4.96 | IC50 | 11000.0 | Preclinical |
| CHEMBL3261430 | 4.85 | IC50 | 14000.0 | Preclinical |
| CHEMBL4202870 | 4.77 | IC50 | 17000.0 | Preclinical |
| CHEMBL4210636 | 4.62 | IC50 | 24000.0 | Preclinical |
| CHEMBL4208517 | 4.54 | IC50 | 29000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 10 | 5.2 |
| single protein format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 1 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 0 | — |