Cyclin-dependent kinase 17 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q00537. Use UniProt Q00537 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q00537 as the stable identity anchor, then attach disease evidence before program review.
Cyclin-dependent kinase 17
Review this target as Cyclin-dependent kinase 17, mapped to UniProt Q00537. Sequence length is 523 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cyclin-dependent kinase 17 as ChEMBL target CHEMBL5790, mapped to UniProt Q00537. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cyclin-dependent kinase 17 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q00537 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cyclin-dependent kinase 17 |
| UniProt Accession | Q00537 |
| Component Type | Protein |
| Sequence Length | 523 aa |
Cyclin-dependent kinase 17
Review this target as Cyclin-dependent kinase 17, mapped to UniProt Q00537. Sequence length is 523 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL384304 | 9.07 | Kd | 0.86 | Clinical |
| CHEMBL445813 | 9.02 | Kd | 0.95 | Clinical |
| CHEMBL296468 | 8.7 | Kd | 2.0 | Preclinical |
| CHEMBL3545085 | 8.3 | Kd | 5.0 | Preclinical |
| CHEMBL428690 | 8.22 | Kd | 6.0 | Clinical |
| CHEMBL1738757 | 8.15 | Kd | 7.0 | Clinical |
| CHEMBL482967 | 8.15 | Kd | 7.0 | Preclinical |
| CHEMBL3128043 | 7.85 | Kd | 14.0 | Preclinical |
| CHEMBL574738 | 7.82 | Kd | 15.0 | Preclinical |
| CHEMBL2028663 | 7.44 | Kd | 36.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 67 | 29 | 6.4 |
| cell-based format | 23 | 0 | — |
| subcellular format | 23 | 19 | 7.0 |
| assay format | 16 | 0 | — |