Glucagon-like peptide 1 receptor · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P32301. Use UniProt P32301 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P32301 as the stable identity anchor, then attach disease evidence before program review.
Glucagon-like peptide 1 receptor
Review this target as Glucagon-like peptide 1 receptor, mapped to UniProt P32301. Sequence length is 463 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Glucagon-like peptide 1 receptor as ChEMBL target CHEMBL5862, mapped to UniProt P32301. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Glucagon-like peptide 1 receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P32301 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glucagon-like peptide 1 receptor |
| UniProt Accession | P32301 |
| Component Type | Protein |
| Sequence Length | 463 aa |
Glucagon-like peptide 1 receptor
Review this target as Glucagon-like peptide 1 receptor, mapped to UniProt P32301. Sequence length is 463 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2158410 | 10.05 | EC50 | 0.09 | Preclinical |
| CHEMBL4749279 | 9.92 | EC50 | 0.12 | Preclinical |
| CHEMBL414357 | 9.85 | IC50 | 0.14 | Approved |
| CHEMBL4066463 | 9.6 | EC50 | 0.25 | Preclinical |
| CHEMBL5208485 | 9.6 | EC50 | 0.25 | Preclinical |
| CHEMBL1092704 | 9.43 | IC50 | 0.37 | Preclinical |
| CHEMBL1092373 | 9.32 | IC50 | 0.48 | Preclinical |
| CHEMBL4751466 | 9.32 | EC50 | 0.48 | Preclinical |
| CHEMBL1092706 | 9.26 | IC50 | 0.55 | Preclinical |
| CHEMBL1092708 | 9.24 | IC50 | 0.58 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 14 | 48 | 6.6 |
| single protein format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 10 | 27 | 6.2 |