Beta-2 adrenergic receptor · SINGLE PROTEIN · Mesocricetus auratus
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As of 2026-09-14Protein identity stays anchored to UniProt P04274. Use UniProt P04274 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P04274 as the stable identity anchor, then attach disease evidence before program review.
Beta-2 adrenergic receptor
Review this target as Beta-2 adrenergic receptor, mapped to UniProt P04274. Sequence length is 418 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-2 adrenergic receptor as ChEMBL target CHEMBL5943, mapped to UniProt P04274. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Beta-2 adrenergic receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Mesocricetus auratus |
| UniProt | P04274 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-2 adrenergic receptor |
| UniProt Accession | P04274 |
| Component Type | Protein |
| Sequence Length | 418 aa |
Beta-2 adrenergic receptor
Review this target as Beta-2 adrenergic receptor, mapped to UniProt P04274. Sequence length is 418 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL524037 | 8.22 | EC50 | 6.0 | Preclinical |
| CHEMBL1160723 | 7.7 | EC50 | 20.0 | Clinical |
| CHEMBL462273 | 7.5 | EC50 | 32.0 | Preclinical |
| CHEMBL1160723 | 6.87 | Ki | 136.0 | Clinical |
| CHEMBL493489 | 6.75 | EC50 | 177.0 | Preclinical |
| CHEMBL524037 | 6.51 | Ki | 311.0 | Preclinical |
| CHEMBL462273 | 6.06 | Ki | 863.0 | Preclinical |
| CHEMBL462274 | 5.96 | EC50 | 1087.0 | Preclinical |
| CHEMBL493489 | 5.64 | Ki | 2296.0 | Preclinical |
| CHEMBL462274 | 5.37 | Ki | 4314.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 9 | 5 | 7.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 5 | 6.1 |